Results 51 to 60 of about 3,913 (266)
Student Perceptions of Textbook Layout and Learnability in Private Schools
Journal of Education and Educational Development, 2015 This research is an exploratory study that investigates students’ perceptions pertinent to textbook layout and organization and their evaluation of the textbook ease of learning.
Alefiyah Hoshangabadwala
doaj
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The Non-Biological Evolution of Grammar: Wh-Question Formation in Germanic
Biolinguistics, 2009 The wh-marking of questions in child English is as early as the appearance of the wh-questions themselves. The wh-marking of questions in child Dutch (and the other Germanic languages) is delayed until the acquisition of articles and free anaphoric ...
Jacqueline van Kampen
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
The Role of Human–Computer Interaction in Shaping User Engagement with E-Commerce Applications
InformaticsThis research aimed to determine the influence of human–computer interaction usability on the behavioral intention and self-reported continued usage intentions of e-commerce applications.
Hasan Razzaqi +3 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
IEEE AccessMachine learning (ML) has been increasingly applied in usability engineering to evaluate its dimensions, such as efficiency, errors, and satisfaction.
Hend Alkhoder, Muna Al-Razgan
doaj +1 more source
Simplicity and the Form of Grammars
Journal of Language Modelling, 2021 The goal of theory construction is explanation: for language, theory for particular languages (grammar) and for the faculty of language FoL (the innate endowment for language acquisition). A primitive notion of simplicity of grammars is number of symbols,
Noam Chomsky
doaj