Results 41 to 50 of about 9,002 (304)

Solving the UG Problem

open access: yesBiolinguistics, 2012
Many generalizations are impossible to learn via primary linguistic data, so they are assumed to be part of our genetic endowment. Generativists have tried to reduce Universal Grammar (UG) to a minimum, in particular by appealing to computational ...
Denis Bouchard
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

“From zero to three hundred” - intensive acquisition techniques for the 300 most frequent content words in Welsh

open access: yesVocabulary Learning and Instruction
Around twenty thousand adult learners enrol onto Welsh language classes each year, but many do not progress beyond Mynediad level (= Entry, CEFR A1).
Tess Fitzpatrick, Steve Morris
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Multiple Grammars and the Logic of Learnability in L2

open access: yesFrontiers in Psychology, 2016
The goal of this article is to enhance the technical description of multi-lingual speakers in terms of a theoryof Multiple Grammars where more than one language utilizes a grammar.
Tom W Roeper
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Usability Analysis of Smart Speakers from a Learnability Perspective for Novel Users

open access: yesApplied System Innovation
Although commercial smart speakers are becoming increasingly popular, there is still much potential for investigation into their usability. In this study, we analyzed the usability of commercial smart speakers by focusing on the learnability of young ...
Toshihisa Doi, Yuki Nishikawa
doaj   +1 more source

Not All Learnable Distribution Classes are Privately Learnable

open access: yesCoRR
We give an example of a class of distributions that is learnable up to constant error in total variation distance with a finite number of samples, but not learnable under $(\varepsilon, δ)$-differential privacy with the same target error. This weakly refutes a conjecture of Ashtiani.
Mark Bun   +3 more
openaire   +3 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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