Results 41 to 50 of about 132,928 (250)

FurMoLi: A Future Query Technique for Moving Objects Based on a Learned Index

open access: yesMathematics
The future query of moving objects involves predicting their future positions based on their current locations and velocities to determine whether they will appear in a specified area.
Jiwei Yang   +5 more
doaj   +1 more source

A Lightweight Graph Neural Network Algorithm for Action Recognition Based on Self-Distillation

open access: yesAlgorithms, 2023
Recognizing human actions can help in numerous ways, such as health monitoring, intelligent surveillance, virtual reality and human–computer interaction. A quick and accurate detection algorithm is required for daily real-time detection. This paper first
Miao Feng, Jean Meunier
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

GLMI: An Efficient Spatiotemporal Index Leveraging Geohash and Piecewise Linear Models for Optimized Query Performance

open access: yesAlgorithms
Spatiotemporal big data contain information in multiple dimensions such as space and time. Spatiotemporal data have the characteristics of large volume, intricate spatiotemporal relationship, and uneven spatiotemporal distribution. Index structure is one
Kun Chen   +4 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

A Learned Index for Exact Similarity Search in Metric Spaces

open access: yes, 2022
Indexing is an effective way to support efficient query processing in large databases. Recently the concept of learned index, which replaces or complements traditional index structures with machine learning models, has been actively explored to reduce ...
Yan, Tingyun   +9 more
core   +2 more sources

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Assessment of the Ecological Impacts of Coal Mining and Restoration in Alpine Areas: A Case Study of the Muli Coalfield on the Qinghai-Tibet Plateau

open access: yesIEEE Access, 2021
Surface mining inevitably impacts the ecological environment, especially in alpine and fragile mining areas. Thus, it is worth discussing the dynamic impact process of mining on regional land use and landscapes. In this study, we took the Muli coalfield,
Dongzhu Yuan   +6 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

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