Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Wage Inequality Within and Between Occupations
Nordic Journal of Working Life Studies, 2017 Western countries, including Scandinavian nations, have witnessed an increase in wage inequality over the past decades. Recent studies attribute rising wage inequality in the United States and United Kingdom primarily to between-occupation inequality ...
Håvard Helland, Thijs Bol, Ida Drange
doaj +1 more source
MODERATING EFFECT OF TRAINING TRANSFER ON THE DETERMINANTS OF ENTREPRENEURIAL PERFORMANCE AMONG MICRO, SMALL AND MEDIUM ENTERPRISES (MSMEs) OWNERS IN LAGOS STATE, NIGERIA [PDF]
, 2017 Despite the significance and contributions of micro, small and medium ente1prises (MSMEs) ·to the national economy, many problems and constraints still exist in promoting their development and growth ·which invariably affect the pe1formance of the O ...
Awe, Kayode Obafemi +1 more
core
Pengembangan Model Bimbingan Teknis Berkelanjutan dalam Meningkatkan Kompetensi Tutor Paket C [PDF]
, 2015 This study aims at finding a model of Sustainable Technical Assistance that can improve the Package C tutors\u27competence. The alternative model selected to achieve the research objective was by developing a model based on Sustainable Technical ...
Sutisna, A. (Anan)
core +2 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
On Different Tracks? Gender, Professional Strategies, and Early Career Wage Gaps
Nordic Journal of Working Life Studies, 2017 A longstanding notion in labor market theory is that women accommodate family responsibilities in their occupational and job choices. Utilizing a survey of newly graduated highly educated men and women in five occupations in Sweden (n≈2400), the article ...
Anne Grönlund
doaj +1 more source
Study of the Relationship between Communication Competence and Heart Rate Variability among International Postgraduate Students of a Malaysian Public University [PDF]
, 2016 Communication competence is among the main skills that enable individuals to conduct fruitful interactions with different people. This study was carried out to examine the relationship between communication competence and heart rate variability (HRV ...
Muhammad Nubli, Abdul Wahab +1 more
core
The impact of entrepreneurship education on entrepreneurship competencies and intentions: an evaluation of the junior achievement student mini-company program [PDF]
, 2008 This paper analyzes the impact of a leading entrepreneurship education program on college students' entrepreneurship competencies and intentions using an instrumental variables approach in a difference-in-differences framework.
IJsselstein, Auke +2 more
core +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
The effects of pressure dependent constitutive model to simulate concrete structures failure under impact loads [PDF]
, 2017 The main objective of this paper is to explore the effect of confining pressure in the compression and tension zone by simulating the behaviour of reinforced concrete/mortar structures subjected to the impact load.
Kamarudin, A. F. +4 more
core +3 more sources