Results 41 to 50 of about 407,217 (307)

The Learning Curve in Skullbase Surgery Part 2–From the Microsurgical Lab Training to the Operative Room

open access: yesBrazilian Neurosurgery, 2022
In this second part, the authors review and suggest a methodology for studies in skull base surgery and training in microsurgical laboratory, based on their experiences and reflections.
Gustavo Rassier Isolan   +10 more
doaj   +1 more source

Learning Curve Theory

open access: yesCoRR, 2021
Recently a number of empirical "universal" scaling law papers have been published, most notably by OpenAI. `Scaling laws' refers to power-law decreases of training or test error w.r.t. more data, larger neural networks, and/or more compute. In this work we focus on scaling w.r.t. data size $n$.
openaire   +2 more sources

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Endoscopic sleeve gastroplasty: the learning curve

open access: yesEndoscopy International Open, 2017
Background and study aims Endoscopic sleeve gastroplasty (ESG) is gaining traction as a minimally invasive bariatric treatment. Concern that the learning curve may be slow, even among those proficient in endoscopic suturing, is a barrier to widespread ...
Christine Hill   +11 more
doaj   +1 more source

A goat eye, wet lab model for training in Descemet membrane endothelial keratoplasty

open access: yesIndian Journal of Ophthalmology, 2023
Here we describe a new, non-human, ex-vivo model (goat eye model) for training surgeons in DMEK surgeons. In a wet lab setting, goat eyes were used to obtain a pseudo-DMEK graft of 8 mm from the goat lens capsule that was injected into another goat eye ...
Nidhi Gupta   +6 more
doaj   +1 more source

The learning curve in a competitive industry [PDF]

open access: yes, 1994
We consider the learning curve in an industry with free entry and exit, and price-taking firms. A unique equilibrium exists if the fixed cost is positive.
Rasmusen, Eric   +2 more
core  

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

The learning curve for robot-assisted radical cystectomy with total intracorporeal urinary diversion based on radical cystectomy pentafecta

open access: yesFrontiers in Oncology, 2022
ObjectiveTo analyze the learning curve for robot- assisted radical cystectomy (RARC) with total intracorporeal urinary diversion (ICUD) in terms of both time efficiency and quality of surgery based on radical cystectomy (RC)-pentafecta.Patients and ...
Tae Il Noh   +5 more
doaj   +1 more source

Learning curve of uniportal video-assisted lobectomy: Analysis of 15-month experience in a single center

open access: yes, 2018
Background: Uniportal video-assisted thoracoscopic (U-VATS) lobectomy has been becoming the technique of choice in an increasing number of centers.
Meacci, Elisa   +8 more
core   +1 more source

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