Results 61 to 70 of about 1,171,311 (279)

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu   +10 more
wiley   +1 more source

The Climate Change Learning Curve [PDF]

open access: yes
The key element in the tension between those who believe climate change is an issue and those who do not is essentially the question of whether we are merely in a long period of shock-induced above average temperatures or if we have led to this increase ...
Andrew J. Leach
core  

Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito   +14 more
wiley   +1 more source

Learning micro incision surgery without the learning curve

open access: yesIndian Journal of Ophthalmology, 2008
We describe a method of learning micro incision cataract surgery painlessly with the minimum of learning curves. A large-bore or standard anterior chamber maintainer (ACM) facilitates learning without change of machine or preferred surgical technique ...
Thomas Ravi, Navin Shoba, Parikh Rajul
doaj  

SHOULD A PRODUCTION RATE VARIABLE BE INCLUDED IN MILITARY AIRCRAFT LEARNING CURVES? EMPIRICAL EVIDENCE FROM THE UNITED STATES AIR FORCE [PDF]

open access: yesJournal of Defense Resources Management, 2023
Learning curves are a core analytical method employed by cost analysts to estimate weapon system production costs. This study examines United States Air Force aircraft programs and compares the traditional (e.g., Unit Theory) learning curve model to a
Caleb J. AHERN   +5 more
doaj  

Sophocles’ Learning Curve

open access: yes, 2007
Abstract Two of the most influential mid-20th-century discussions of Sophocles' style operated by trying to fit the surviving plays to the threefold scheme; the most recent, and very thorough, discussion of The Language of Sophocles (Budelmann (2000) ), cites it in the third sentence of the first page.
openaire   +2 more sources

Guidelines for application of learning/cost improvement curves [PDF]

open access: yes
The differences between the terms learning curve and improvement curve are noted, as well as the differences between the Wright system and the Crawford system.
Delionback, L. M.
core   +1 more source

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel   +8 more
wiley   +1 more source

Observational-Interventional Priors for Dose-Response Learning [PDF]

open access: yes, 2016
Controlled interventions provide the most direct source of information for learning causal effects. In particular, a dose-response curve can be learned by varying the treatment level and observing the corresponding outcomes. However, interventions can be
Silva, Ricardo
core   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang   +6 more
wiley   +1 more source

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