Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Coaching as an educator: Critical elements in a faculty development program
Introduction: Coaching has gained acceptance in the education field as a way to enable learners to achieve their fullest potential. In the endeavor to set up a coaching ecosystem in our university, we started by equipping our educators with fundamental ...
Sok Mui Lim +2 more
doaj +1 more source
Development of a graphical model of causal gene regulatory networks using medical big data and Bayesian machine learning [PDF]
Sung Bae Park, Changwon Yoo
openalex +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Unpacking locally led research and evaluation through the lens of collaborative autoethnography
Background: Evaluation in Africa and the Global South has been driven by external, often foreign, actors and focused on meeting donor funding needs, conducted through the lens of ‘others’ other than the affected populations.
Clement Sefa-Nyarko +6 more
doaj +1 more source
Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson +2 more
wiley +1 more source
The factor of failure in Arabic language learning in Indonesia is the lack of activities in language learning. One of language learning activities is identifying meaning or word meaning and phrase in dictionary.
R. Umi Baroroh +2 more
doaj +1 more source
Multi-scale discrepancy adversarial network for crosscorpus speech emotion recognition
Background: One of the most critical issues in human-computer interaction applications is recognizing human emotions based on speech. In recent years, the challenging problem of cross-corpus speech emotion recognition (SER) has generated extensive ...
Wanlu Zheng, Wenming Zheng, Yuan Zong
doaj +1 more source
Holistic Learning: A workforce development paradigm [PDF]
The development of workforce knowledge, skills and attitudes are widely acknowledged in extant literature as being pivotal levers to deliver process improvement and efficiency.
Adjaie John, Godfaurd +3 more
core +1 more source
Content-driven design and architecture of E-learning applications [PDF]
E-learning applications combine content with learning technology systems to support the creation of content and its delivery to the learner. In the future, we can expect the distinction between learning content and its supporting infrastructure to become
Pahl, Claus
core +1 more source

