Results 81 to 90 of about 6,121,974 (286)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

The effects of the design and development of a chemistry curriculum reform on teachers’ professional growth: a case study [PDF]

open access: yes, 2010
A curriculum innovation requires new learning material for students and a preparation program for teachers, in which teacher learning is a key ingredient.
Coenders, Fer   +3 more
core   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

The Relationship Development and Learning Organization Dimensions. [PDF]

open access: yes, 2011
This research examined the relationship among learning organization dimensions, leadership development, employee development, and their interactions with two demographic variables (gender and ethnicity) in the context of libraries.
Haley, Connie K., Dr.   +1 more
core   +1 more source

Simulation modelling: Educational development roles for learning technologists [PDF]

open access: yes, 2002
Simulation modelling was in the mainstream of CAL development in the 1980s when the late David Squires introduced this author to the Dynamic Modelling System.
Riley, David
core   +2 more sources

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

A Brain-Computer Interface Based on a Few-Channel EEG-fNIRS Bimodal System

open access: yesIEEE Access, 2017
With the development of the wearable brain-computer interface (BCI), a few-channel BCI system is necessary for its application to daily life. In this paper, we proposed a bimodal BCI system that uses only a few channels of electroencephalograph (EEG) and
Sheng Ge   +7 more
doaj   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

open access: yesAging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss   +12 more
wiley   +1 more source

Choose Your Own Adventure! An empirical study on gamification of postgraduate learning on research project design

open access: yesJournal of Play in Adulthood
It is difficult to teach complex topics such as academic research to student cohorts who are widely heterogeneous in prior knowledge, learning goals, and learning preferences.
Daisy Abbott
doaj   +2 more sources

A framework for developing and implementing an online learning community [PDF]

open access: yes, 2011
Developing online learning communities is a promising pedagogical approach in online learning contexts for adult tertiary learners, but it is no easy task.
Cowie, Bronwen, Khoo, Elaine G.L.
core   +2 more sources

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