Results 71 to 80 of about 16,183,910 (292)
Scheduling with Group Technology, Resource Allocation, and Learning Effect Simultaneously
MathematicsThis paper studies the single-machine group scheduling problem with convex resource allocation and learning effect. The number of jobs in each group is different, and the corresponding common due dates are also different, where the processing time of ...
Ming-Hui Li +3 more
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Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Applied Sciences, 2020 Occlusion is a fundamental subject in dental education, and occlusal adjustment is clinically essential in daily dental practices. This study aimed to assess the effects of computer-based 3D simulations on learner responses and learning effect on the ...
Hai Yen Mai, Hang-Nga Mai, Du-Hyeong Lee
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
The Effect of the Degree of Anxiety of Learners during the Use of VR on the Flow and Learning Effect
Applied Sciences, 2020 Virtual reality (VR) learning content that provides negative experiences makes learners anxious. Thus, experimental research was conducted to determine how anxiety felt by learners using VR impacts learning.
Chongsan Kwon
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CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
The professional learning of Scotland’s Adult Educators
, 2018 First paragraph: Following the publication of Adult Learning in Scotland: Statement of Ambition in 2014, four national working groups were set up to take forward the Scottish Government’s vision to establish world leading adult learning in Scotland. This
Galloway, Sarah
core
Hybrid Multi-Objective Artificial Bee Colony for Flexible Assembly Job Shop with Learning Effect
MathematicsThe flexible job shop scheduling problem is a typical and complex combinatorial optimization problem. In recent years, the assembly problem in job shop scheduling problems has been widely studied.
Zhaosheng Du, Junqing Li, Jiake Li
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