Results 21 to 30 of about 803,445 (216)
Learning Health Systems, 2022 Learning Health Systems (LHS) require a workforce with specific knowledge and skills to identify and address healthcare quality issues, develop solutions to address those issues, and sustain and spread improvements within and outside the organization ...
Sue S. Feldman +4 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Implementation Science CommunicationsBackground Implementation science as a field is rapidly advancing. Moreover, implementation science plays a pivotal role in driving learning health systems to better realize health outcomes and impact for our communities.
Stephanie P. Brooks +6 more
doaj +1 more source
Journal of Clinical and Translational ScienceObjectives/Goals: The Standards for Reporting Implementation Studies (StaRI) are the Enhancing the Quality and Transparency of Health Research (EQUATOR) Network 27-item checklist for Implementation Science.
Christopher Carpenter +7 more
doaj +1 more source
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Learning Health SystemsBackground Communities of practice support evidence‐based practice and can be, in and of themselves, applied learning spaces in organizations. However, the variety of ways that communities of practice can support learning health systems are poorly ...
Stephanie P. Brooks +5 more
doaj +1 more source
General orders for the embedded researcher: Moorings for a developing profession
Learning Health Systems, 2021 Learning health systems increasingly welcome embedded researchers as stakeholders poised to inform evidence‐based practice. While care systems are potentially familiar with the embedded researcher tools and techniques, care systems may less frequently ...
Matthew F. Hudson
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Putting the network to work: Learning networks in rapid response situations
Learning Health Systems, 2021 Introduction The rapid response to COVID‐19 has necessitated infrastructural development and reorientation in order to safely meet patient care needs. Methods A qualitative case study was constructed within a larger ethnographic field study.
Alexandra H. Vinson
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source