Paternal Circadian Disruption Impairs Offspring Cognition via Sperm microRNAs
Paternal circadian disruption remodels the sperm small RNA payload, elevating miR‐92a‐3p/miR‐25‐3p levels and perturbing early embryonic gene regulatory programs. Microinjection experiments and single‐embryo transcriptomics reveal sex‐specific developmental vulnerabilities, ultimately impairing offspring hippocampal synaptic plasticity and cognition ...
Kexin Zou +22 more
wiley +1 more source
Learning motivation among international students: the role of demographic factors. [PDF]
Chuang TF, Lin MH, Wu TC, Chuang MD.
europepmc +1 more source
De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li +23 more
wiley +1 more source
The impact of trait anxiety on academic procrastination among college students: the mediating role of academic self-efficacy and the moderating role of autonomous learning motivation. [PDF]
Fan J +5 more
europepmc +1 more source
Rotation of Crystal Seed During Early Stages of Growth Reveals the Anisotropy of Glass Matrix
Molecular dynamics simulations reveal that crystal seeds can spontaneously rotate within glass at high temperatures due to anisotropic forces at the glass‐crystal interface. This rotation challenges the long‐held view of glass as an isotropic solid and highlights how atomic‐scale inhomogeneities can influence crystal growth and microstructure of LiNbO3‐
R. Thapa +4 more
wiley +1 more source
The relationship between Chinese medical students' learning motivation and learning engagement: a network analysis. [PDF]
Wang D +4 more
europepmc +1 more source
Abstract After more than 20 years in various sales and marketing roles, I have recently changed careers to lecturing business studies subjects within the HETAC framework. I decided to use the opportunity to conduct an action research project to address student engagement and explore strategies to encourage the students to take ownership of the learning
openaire +1 more source
Geometry and connectivity are complementary structures, which have demonstrated their ability to represent the brain's functional activity. This study evaluates geometric and connectome eigenmodes as biologically informed constraints for EEG source localization.
Pok Him Siu +6 more
wiley +1 more source
HoloPatient-based simulation education to improve nursing students' learning motivation and attitude: a mixed methods study. [PDF]
Kang Y, Lee I.
europepmc +1 more source
This study reveals that maternal antibiotic exposure prior to conception disrupts intergenerational gut microbial succession. By enhancing maternal‐offspring microbial transmission, altering microbial developmental trajectories and increasing selective pressures during community assembly, these disturbances lead to persistent gut mucosal immaturity and
Yuzhu Chen +8 more
wiley +1 more source

