Results 141 to 150 of about 664,687 (298)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling   +16 more
wiley   +1 more source

How to make a step towards future education. Teaching/learning methods in higher education for the 21st century

open access: yesKultura i Wychowanie
 The rapid development of the world requires new improvements in every field of life and demands new knowledge and skills from each worker. The employers expect a workforce with a new set of skills.
Dace Siliņa, Kamila Witerska
doaj   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao   +7 more
wiley   +1 more source

The Learning Outcome in Higher Education: Time to Think Again? [PDF]

open access: yes, 2011
As a head of an academic development and practice unit it is with some trepidation that I set out to write this critique of learning outcomes. For the learning outcome has become the bed-rock of the infra-structure that determines quality assurance ...
Scott, Ian
core  

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi   +8 more
wiley   +1 more source

Penerapan Model Pembelajaran Problem Based Learning Plus Lembar Mudzakarah Dalam Meningkatkan Hasil Belajar Siswa di MAN Kota Cimahi

open access: yesCommunity Empowerment
The learning conditions in the mawaris material, especially in the internal heirs and their sections, previously used a one-way learning style with a very high percentage of the lecture method, this made the learning situation not show high enthusiasm in
Iman Zaelani
doaj   +1 more source

Authoring for Re-Use in Outcome-oriented Learning Scenarios [PDF]

open access: yes, 2010
Klemke, R., & Schmitz, B. (2010, 27-28 September). Authoring for Re-Use in Outcome-oriented Learning Scenarios. Workshop presentation at the Fourth International Workshop on Search and Exchange of e-le@rning Materials (SE@M’10), Barcelona, Spain.Content ...
Schmitz, Birgit   +2 more
core  

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Home - About - Disclaimer - Privacy