Results 61 to 70 of about 6,606,150 (275)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Learning Styles: Moving Forward from the Myth

Canadian Journal for New Scholars in Education, 2019
Learning styles attempt to describe individual differences among students by identifying students’ preferences in how they learn, and adapting their learning to accommodate that style.
Andrea Antoniuk
doaj  

Automatic Student Modelling for Detection of Learning Styles and Affective States in Web Based Learning Management Systems

IEEE Access, 2019
In traditional learning environments, it is easy for a teacher to get an accurate and deep understanding about how students are learning and undertaking tasks.
Farman Ali Khan, Awais Akbar, Muhammad Altaf, Shujaat Ali Khan Tanoli, Ayaz Ahmad   +4 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

ANALISIS TINGKAT KEMAMPUAN BERPIKIR KREATIF MATEMATIS PESERTA DIDIK DITINJAU DARI GAYA BELAJAR KELAS VII SMP

Aksioma: Jurnal Program Studi Pendidikan Matematika, 2019
This research is motivated by observations at Muhammadiyah junior high school number 3 in Bandar Lampung that ability of students to solve mathematical problems have different thinking skills, diverse learning styles possessed by students in absorbing ...
Dwi Purwanti, Jamal Fakhri, Hasan Sastra Negara   +2 more
doaj   +1 more source

The Analysis of Learning Styles and Their Relationship to Academic Achievement in Medical Students of Basic Sciences Program [PDF]

Research and Development in Medical Education, 2013
Introduction: Learning style is an individual’s preferred method of encountering information in specific situations in order to acquire knowledge, skills and attitudes through study or experience.
Reza Ghaffari, Fariba Salek Ranjbarzadeh, Eskandar Fathi Azar, Susan Hassanzadeh, Naser Safaei, Parisa Golanbar, Hossein Mazouchian, Elham Abbasi   +7 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source