Results 81 to 90 of about 398,042 (310)

Investigating learning transfer on an adjunct writing course for L2 English speaking trainee teachers

open access: yesInternational Journal of English for Academic Purposes, 2022
This study represents an account and analysis of an adjunct writing course designed to assist L2 English speaking teachers with the written assignments on a Trinity College London CertTESOL course.
Matthew Gordon
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Back to the workplace: How organisations can improve their support for management learning and development [PDF]

open access: yes, 2004
This paper explores how organisations can become more sophisticated at supporting transfer of learning, by identifying the perceived barriers and facilitators to transfer of learning, by examining a range of individual characteristics and workplace ...
James, Kim   +5 more
core   +1 more source

Simple Synthetic Data as Source Domain for Transfer Learning to Remote Sensing as a Target Domain

open access: yes, 2023
Deep Learning continues to grow as a prevalent toolset among multiple disciplines, including Remote Sensing and image analysis. Correspondingly, to more easily apply the deep neural networks to different subject matter domains, Transfer Learning, from ...
Shaw, Brian L
core   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Transfer of learning and the cultural matrix: the interrelationship of culture, beliefs, and learning [PDF]

open access: yes, 2015
This study, conducted in an international college in Thailand, aimed to understand the transfer of learning from an undergraduate academic literacy programme to the disciplines.
Green, Jonathan Henry
core  

Q-learning model of insight problem solving and the effects of learning traits on creativity

open access: yesFrontiers in Psychology
Despite the fact that insight is a crucial component of creative thought, the means by which it is cultivated remain unknown. The effects of learning traits on insight, specifically, has not been the subject of investigation in pertinent research.
Tsutomu Harada
doaj   +1 more source

Learning to Selectively Transfer [PDF]

open access: yesProceedings of the Twelfth ACM International Conference on Web Search and Data Mining, 2019
Accepted to WSDM ...
Chen Qu 0001   +7 more
openaire   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

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