Results 101 to 110 of about 18,179 (262)
Inverse Designing Surface Curvatures by Deep Learning
Smooth and curved microstructural topologies found in nature—from soap films to trabecular bone—have inspired several mimetic design spaces for architected metamaterials and bio‐scaffolds.
Yaqi Guo, Saurav Sharma, Siddhant Kumar
doaj +1 more source
ABSTRACT Deep‐technology ventures, particularly in medical artificial intelligence (AI), face a persistent “valley of death” where promising innovations fail to find viable business models despite technical merit. While the NSF I‐Corps program addresses this through structured customer discovery, little empirical research validates how specific market ...
Amil Khanzada, Takuji Takemoto
wiley +1 more source
Systematic Review of the Huntington's Disease Drug Development Pipeline, 2014 to 2025
Abstract Background In the past decade, significant advances have improved our understanding of the mechanisms underlying HD pathobiology leading to several putative therapeutic targets for HD. Objective The aim was to describe the Huntington's disease (HD) drug development clinical pipeline.
Pavlina Konstantinova +5 more
wiley +1 more source
Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley +1 more source
Care and COVID 19: Lessons for liberals and neoliberals
Abstract Within the liberal political traditions, care is regarded as a private matter, a problem of ethics rather than justice. Social justice is framed as an issue of economics (re/distribution), culture (recognition) and/or politics (representation).
Kathleen Lynch
wiley +1 more source
ABSTRACT The purpose of this paper is to develop foundational propositions designed to reflect success factors in the recruitment and retention of volunteers for future longevity. Using insights gathered from three universities' experiences of student volunteering during COVID‐19, plus capturing the experiences of volunteer involving organizations, we ...
Ingrid O'Brien +5 more
wiley +1 more source
This article examines the methodological choices made for a research study into Health Systems Leadership. Reflections on key learnings are provided as a way of offering insight for researchers navigating these decisions for the first time. Embarking on
Rebecca Kate George +2 more
doaj
Abstract Volunteers have been involved in nature observations for decades through citizen science initiatives, providing large data sets as well as problem identification that allow a more complete understanding of many natural phenomena. Although communication is a core component in citizen science, the key factors that determine its effectiveness in ...
Kristiina Gibson +18 more
wiley +1 more source
Supporting Students on the Right PATH in Catholic Schools
ABSTRACT Low‐income, first‐generation students can benefit from programs designed to reduce the college access opportunity gap. This paper describes the PATH program, operating in two Catholic grade schools in the Southwest in partnership with the University of Notre Dame.
Monica J. Kowalski, Alec Torigian
wiley +1 more source
Designing Community Governance – Learnings from DAOs
This work examines how decentralised autonomous organisations (DAOs) can improve transparency, fairness, and inclusivity in community-based decision-making, using the case of research grant allocation within a university community in Switzerland.
Michael Lustenberger +2 more
doaj +1 more source

