Results 81 to 90 of about 50,965,468 (254)

Safety and Tolerability of Givinostat: Evidence From Real‐World and Clinical Practice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The aim of our study was to establish the prevalence of adverse events in a real‐world setting in boys living with Duchenne muscular dystrophy (DMD) treated with givinostat as part of an Expanded Access Program (EAP) in Italy. Methods The cohort included 90 ambulant boys, with age when treatment started between 6 and 23 years (mean ...
Marika Pane, Anna Capasso, Chiara Arpaia, Adele D’Amico, Emilio Albamonte, Federica Trucco, Maria Sframeli, Riccardo Masson, Francesca Magri, Luca Bello, Romina Venditti, Claudia Dosi, Michela Catteruccia, Michele Tosi, Claudio Bruno, Sonia Messina, Giacomo Comi, Elena Pegoraro, Valeria A. Sansone, Eugenio Mercuri   +19 more
wiley   +1 more source

Predicted accuracy of and response to genomic selection for new traits in dairy cattle

Animal, 2013
Genomic selection relaxes the requirement of traditional selection tools to have phenotypic measurements on close relatives of all selection candidates. This opens up possibilities to select for traits that are difficult or expensive to measure.
M.P.L. Calus, Y. de Haas, M. Pszczola, R.F. Veerkamp   +3 more
doaj   +1 more source

Comprehensive Assessment of Arterial, Tissue, and Venous Collaterals for Evaluating the Infarct Growth Rate: The Multimodal Collateral Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Collaterals are crucial factors that influence the infarct growth rate (IGR). We aimed to determine whether a comprehensive multimodal collateral score (MCS), incorporating collateral assessment at the arterial, tissue, and venous levels, is associated with functional independence and provides incremental prognostic value over ...
Giorgio Busto, Umberto Pensato, Ilaria Casetta, Giorgio U. Marcello, Angelo Barra, Anna Poggesi, Edoardo Carlesi, Sara Mancini, Andrea Ginestroni, Vittorio Miele, Alessandro Padovani, Andrea Morotti, Enrico Fainardi   +12 more
wiley   +1 more source

Zero range condensation at criticality [PDF]

, 2011
Zero-range processes with decreasing jump rates exhibit a condensation transition, where a positive fraction of all particles condenses on a single lattice site when the total density exceeds a critical value.
Armendáriz, I., Grosskinsky, S., Armendáriz, Inés, Grosskinsky, Stefan, Loulakis, M., Loulakis, Michail   +5 more
core   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

A Finite-Sample Deviation Bound for Stable Autoregressive Processes

, 2020
In this paper, we study non-asymptotic deviation bounds of the least squares estimator in Gaussian AR(n) processes. By relying on martingale concentration inequalities and a tail-bound for χ2 distributed variables, we provide a concentration bound for ...
González, Rodrigo A.,, Rojas, Cristian R.,   +1 more
core  

Zero echo time MRI with deep learning reconstruction and chemical shift correction for detecting osteolytic myeloma lesions

European Radiology Experimental
Objective We compared three magnetic resonance imaging (MRI) sequences—native zero echo time (ZTE), deep learning (DL)-chemical shift correction (CSC) reconstructed ZTE (ZTE-DLCSC), and gradient-echo black bone (BB)—in detecting osteolytic multiple ...
Darius Lepot, Caroline Chabot, Gaëtan Duchêne, Sagar Mandava, Maggie Fung, Julie Poujol, Marie-Christiane Vekemans, Perrine Triqueneaux, Nina Watté, Olivier Gheysens, Nicolas Michoux, Frédéric E. Lecouvet   +11 more
doaj   +1 more source

Social Deprivation Index Is Associated with 90-Day Emergency Department Revisits, but Not Admission, for Acute Heart Failure

Western Journal of Emergency Medicine
Background: Prevalence of heart failure is increasing, with an associated rise in emergency department (ED)-related care. Social determinants of health (SDoH) are associated with adverse health outcomes, but the extent to which they influence ED use for ...
Robert R. Ehrman, Nicholas E. Harrison, Brian D. Haber, Steven J Korzeniewski, Mark J. Favot, Lyudmila Khait, Phillip D. Levy   +6 more
doaj   +1 more source

A New Method for the Assessment of Spatial Accuracy and Completeness of OpenStreetMap Building Footprints

ISPRS International Journal of Geo-Information, 2018
OpenStreetMap (OSM) is currently the largest openly licensed collection of geospatial data, widely used in many projects as an alternative to or integrated with authoritative data.
Maria Antonia Brovelli, Giorgio Zamboni
doaj   +1 more source

Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle, Andreas Leha, Volker Limmroth, Wolfram Windisch, Maximilian Zimmermann   +4 more
wiley   +1 more source