Results 111 to 120 of about 10,133,028 (343)
Heterotropic regulation and negative homotropic cooperativity
FEBS Open Bio, EarlyView.We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea +5 more
wiley +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
FEBS Open Bio, EarlyView.GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
, 2003 aerial view, sited on a former trolley yard, Trolley Square is a 40-unit, affordable, mixed-use project that defines a new standard for beautiful and environmentally responsible urban housing.
Davis Square Architects
core
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
FEBS Open Bio, EarlyView.Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source
Two-stage least square regressions.
, 2022 Two-stage least square regressions.
Tamer Elsheikh (14265969) +3 more
core +1 more source
A minimal cellulosome‐like system in Cellulosilyticum lentocellum
FEBS Open Bio, EarlyView.Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
A methodological exploration to determine transportation disadvantage variables: the partial least square approach [PDF]
, 2015 Determining the key variables of transportation disadvantage remains a great challenge as the variables are commonly selected using ad-hoc techniques. In order to identify the variables, this research develops a transportation disadvantage framework by ...
Yigitcanlar, Tan, Rashid, Kushairi
core +1 more source
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
FEBS Open Bio, EarlyView.MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
Improved least mean square algorithm based in satellite multi-beamforming
Tongxin xuebao, 2017 High-throughput satellites use multi-beam technology to achieve polarization isolation and spatial isolation to reuse frequency resources,resulting in increased traffic capacity,but this presents a higher demand for fast adaptive beamforming algorithms ...
Yu-meng ZHANG +3 more
doaj +2 more sources
Data Fitting Based on Genetic Programming and Least Square Method
Chemical Engineering Transactions, 2015 Traditional data fitting techniques usually require estimating basis function and they are specific for different application areas. Based on dynamic characteristics of genetic programming, a two-phase data fitting algorithm is proposed.
P.C. Meng, W.S. Yin, Z.X. Jiang, Y.Z. Li
doaj +1 more source