Results 91 to 100 of about 4,861,455 (309)

Optical Fiber Vibration Sensor Using Least Mean Square Error Algorithm

open access: yesSensors, 2020
In order to enhance the signal-to-noise ratio (SNR) of a distributed optical fiber vibration sensor based on coherent optical time domain reflectometry (COTDR), a high extinction ratio cascade structure of an acousto-optic modulator and semiconductor ...
Yu Wang   +6 more
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Coupled Harmonic Admittance Identification Based on Least Square Estimation

open access: yesEnergies, 2018
Norton equivalent circuit is a commonly used model in estimating harmonic current emissions of harmonic sources. It however cannot reflect the mutual coupling relationships among voltage and current in different harmonic orders. This paper proposes a new
Yaqiong Li   +4 more
doaj   +1 more source

EEG signal classification based on simple random sampling technique with least square support vector machine

open access: yes, 2011
This paper proposes a new approach based on Simple Random Sampling (SRS) technique with Least Square Support Vector Machine (LS-SVM) to classify two-class of electroencephalogram (EEG) signals.
Wen, Peng, Li, Yan
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Copley Square

open access: yes, 2013
Aerial view, from the top of the Prudential Tower, looking down and northeast, with Trinity Church at center (by H.H. Richardson); Copley Square, named for the American portraitist John Singleton Copley (1738-1815), is located in the Back Bay ...
Copley Square Centennial Committee
core  

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

open access: yesMolecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis   +20 more
wiley   +1 more source

Comportamento estocástico do algoritmo kernel least-mean-square [PDF]

open access: yes, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia Elétrica.Algoritmos baseados em kernel têm-se tornado populares no processamento não-linear de sinais.
Parreira, Wemerson Delcio
core  

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

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