Results 81 to 90 of about 10,133,028 (343)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Regularized Least Square Regression with Unbounded and Dependent Sampling

open access: yesAbstract and Applied Analysis, 2013
This paper mainly focuses on the least square regression problem for the -mixing and -mixing processes. The standard bound assumption for output data is abandoned and the learning algorithm is implemented with samples drawn from dependent sampling ...
Xiaorong Chu, Hongwei Sun
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Moving least square–one dimensional integrated radial basis function networks for time dependent problems

open access: yes, 2011
This paper presents a new numerical procedure for time-dependent problems. The partition of unity method is employed to incorporate the moving least square and one-dimensional integrated radial basis function networks techniques in an approach (MLS-1D ...
Ngo-Cong, D.   +7 more
core   +1 more source

NARX-based nonlinear system identification using orthogonal least squares basis hunting [PDF]

open access: yes, 2008
An orthogonal least squares technique for basis hunting (OLS-BH) is proposed to construct sparse radial basis function (RBF) models for NARX-type nonlinear systems.
Wang, X.X.   +2 more
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

PREDIKSI WAKTU KETAHANAN HIDUP DENGAN METODE PARTIAL LEAST SQUARE

open access: yesE-Jurnal Matematika, 2013
Coronary heart disease is caused due to an accumulation of fat on the inside walls of blood vessels of the heart (coronary arteries). The factors that had led to the occurrence of coronary heart disease is dominated by unhealthy lifestyle of patients ...
PANDE PUTU BUDI KUSUMA   +1 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Least Square Approach to Out-of-Sample Extensions of Diffusion Maps

open access: yesFrontiers in Applied Mathematics and Statistics, 2019
Let X = X ∪ Z be a data set in ℝD, where X is the training set and Z the testing one. Assume that a kernel method produces a dimensionality reduction (DR) mapping 𝔉: X → ℝd (d ≪ D) that maps the high-dimensional data X to its row-dimensional ...
Jianzhong Wang
doaj   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

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