Results 81 to 90 of about 4,861,455 (309)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Least-square means and standard error of semen quality traits of different genotypes in the INCENP gene of Chinese Holstein bulls.

, 2016
Least-square means and standard error of semen quality traits of different genotypes in the INCENP gene of Chinese Holstein bulls.
Qiang Jiang (764314), Juan Liu (6492), Jinming Huang (390392), Yan Zhang (8098), Changfa Wang (390394), Yan Sun (22436), Chunhong Yang (764312), Jifeng Zhong (312141), Xiuge Wang (764313), Zhihua Ju (390391)   +9 more
core   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Kernael Least Mean Square Algorithm Based on Block Adaptive Filtering [PDF]

Jisuanji gongcheng, 2017
Kernel Least Mean Square(KLMS) algorithm has a good covergence performance in nonlinear systems.But its mean square error gradient is estimated by the instantaneous gradient that results in larger randomness.However,the block adaptive filtering theory ...
ZHAO Zhijin,JIN Mingming
doaj   +1 more source

ANALISIS DAN PERANCANGAN PROGRAM PERBANDINGAN REGRESI ROBUST LEAST MEDIAN SQUARE DENGAN REGRESI ROBUST LEAST TRIMMED SQUARE MENGGUNAKAN METODE BOOTSTRAP [PDF]

, 2009
ANALISIS DAN PERANCANGAN PROGRAM PERBANDINGAN REGRESI ROBUST LEAST MEDIAN SQUARE DENGAN REGRESI ROBUST LEAST TRIMMED SQUARE MENGGUNAKAN METODE BOOTSTRAP - Bootstrap, robust, least median square, least trimmed square, standard ...
WIBISONO, EDWIN
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Least-Square Prediction for Backward Adaptive Video Coding

EURASIP Journal on Advances in Signal Processing, 2006
Almost all existing approaches towards video coding exploit the temporal redundancy by block-matching-based motion estimation and compensation. Regardless of its popularity, block matching still reflects an ad hoc understanding of the relationship ...
Li Xin
doaj   +1 more source

METODE LEAST SQUARE UNTUK PREDIKSI PENJUALAN SARI KEDELAI ROSI

Simetris: Jurnal Teknik Mesin, Elektro dan Ilmu Komputer, 2016
Sari kedelai Rosi setiap hari memproduksi sari kedelai yang akan disalurkan ke tiga tempat yaitu warung A, B dan C. Penjualan di tiga tempat tersebut setiap harinya mengalami naik turun, akibatnya tidak jarang hasil produksi banyak yang tidak terjual ...
Fajar Rohman Hariri
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Identifikasi Sistem Plant Suhu dengan Metode Recursive Least Square

Jurnal EECCIS (Electrics, Electronics, Communications, Controls, Informatics, Systems), 2013
Salah satu metode untuk mendapatkan model matematika sistem fisik adalah dengan identifikasi. Pada penelitian ini dilakukan proses identifikasi sistem dengan menggunakan metode Recursive Least Square (RLS) dengan struktur model ARX orde 4.
Goegoes Dwi Nusantoro, M. Aziz Muslim, Teguh Budi W.   +2 more
doaj   +1 more source