Results 71 to 80 of about 10,133,028 (343)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Comportamento estocástico do algoritmo kernel least-mean-square [PDF]

open access: yes, 2012
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia Elétrica.Algoritmos baseados em kernel têm-se tornado populares no processamento não-linear de sinais.
Parreira, Wemerson Delcio
core  

Least-square means of moisture, pH, and nicotine concentrations for snus categorized by region and product type.

open access: yes, 2020
Least-square means of moisture, pH, and nicotine concentrations for snus categorized by region and product type.
Hang T. Tran (8308548)   +10 more
core   +1 more source

MENGATASI HETEROSKEDASTISITAS PADA REGRESI DENGAN MENGGUNAKAN WEIGHTED LEAST SQUARE

open access: yesE-Jurnal Matematika, 2015
In the regression analysis we need a method to estimate parameters to fulfill the BLUE characteristic. There are assumptions that must be fulfilled homoscedasticity one of which is a condition in which the assumption of error variance is constant (same),
PUTU AYU MAZIYYA   +2 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Least square and Kalman based methods for dynamic phasor estimation: a review

open access: yes, 2017
The characterization of sinusoidal signals with time varying amplitude and phase is useful and applicable for many fields. Therefore several algorithms have been suggested to estimate main aspects of these signals. Within no standard approach to test the
J. Khodaparast, M. Khederzadeh
semanticscholar   +1 more source

Faster least squares approximation [PDF]

open access: yesNumerische Mathematik, 2010
Least squares approximation is a technique to find an approximate solution to a system of linear equations that has no exact solution. In a typical setting, one lets $n$ be the number of constraints and $d$ be the number of variables, with $n \gg d$. Then, existing exact methods find a solution vector in $O(nd^2)$ time.
Petros Drineas   +3 more
openaire   +4 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Implementasi Partial Least Square Dalam Pemodelan Indeks Pembangunan Manusia

open access: yesEuclid, 2019
Kondisi pembangunan manusia di suatu wilayah dapat digambarkan dengan perhitungan Indeks Pembangunan Manusia (IPM). Komponen yang membentuk IPM cenderung memiliki korelasi yang kuat antara satu dan yang lain, kondisi ini sering disebut multikolinieritas.
Andrew Donda Munthe   +1 more
doaj   +1 more source

Reversible data hiding using least square predictor via the LASSO

open access: yesEURASIP Journal on Image and Video Processing, 2016
Reversible watermarking is a kind of digital watermarking which is able to recover the original image exactly as well as extracting hidden message. Many algorithms have aimed at lower image distortion in higher embedding capacity.
Hee Joon Hwang   +2 more
semanticscholar   +1 more source

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