Results 51 to 60 of about 13,578,374 (288)
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Moving Least Squares Method for a One-Dimensional Parabolic Inverse Problem
Abstract and Applied Analysis, 2014 This paper investigates the numerical solution of a class of one-dimensional inverse parabolic problems using the moving least squares approximation; the inverse problem is the determination of an unknown source term depending on time.
Baiyu Wang
doaj +1 more source
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
Least squares fitting the three-parameter inverse Weibull density [PDF]
, 2010 The inverse Weibull model was developed by Erto [10]. In practice, the unknown parameters of the appropriate inverse Weibull density are not known and must be estimated from a random sample.
Marušić, Miljenko +5 more
core +1 more source
On the computation of the structured total least squares estimator
, 2004 A class of structured total least squares problems is considered, in which the extended data matrix is partitioned into blocks and each of the blocks is (block) Toeplitz/Hankel structured, unstructured, or noise free.
Van Huffel, S. +2 more
core +1 more source
The Use of Partial Least Squares Method To Remove Multicollinearity [PDF]
المجلة العراقية للعلوم الاحصائية, 2010 In this research the estimation of the regression parameters was clarified using least squares and partial least squares compared with the normal method in terms of its ability to be free from the problem of Multicollinearity between the predictive ...
doaj +1 more source
FEBS Open Bio, EarlyView.Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata +13 more
wiley +1 more source
High performance technique FIR Filter Using Least Squares Method
Journal of Engineering and Sustainable Development, 2008 The FIR filter is the one from the most DSP components used. There are two main approaches to design of FIR, first using the windows that have simple mathematics calculations but its results are not optimal.
Wisam Haitham Abbood
doaj
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
FEBS Open Bio, EarlyView.The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source