Results 81 to 90 of about 444,182 (307)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

Analysis of microelectromechanical systems (MEMS) devices by the meshless point weighted least-squares method [PDF]

open access: yes, 2007
In this paper, the characteristics of microelectromechanical systems (MEMS) devices are analyzed by a meshless method—point weighted least-squares (PWLS) method. In the present meshless method, field nodes and collocation points are adopted.
Li, Hua, Wang, Q. X., Lam, K. Y.
core   +1 more source

Improved Least Squares Phase Unwrapping Method Based on Chebyshev Filter

open access: yesApplied Sciences
Phase unwrapping of high phase noise and steep phase gradient has always been a challenging problem in interferometric synthetic aperture radar (InSAR), in which case the least squares (LS) phase unwrapping method often suffers from significant ...
Guoqing Li, Yake Li, Wenyan Liu
doaj   +1 more source

On the Method of Least Squares [PDF]

open access: yesMonthly Notices of the Royal Astronomical Society, 1880
n ...
openaire   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

A note on least squares fitting of signal waveforms [PDF]

open access: yes
Signal waveforms are very fast dampening oscillatory time series composed of exponential functions. The regular least squares fitting techniques are often unstable when used to fit exponential functions to such signal waveforms since such functions are ...
Mishra, SK
core   +1 more source

Orthogonal-least-squares forward selection for parsimonious modelling from data [PDF]

open access: yes, 2009
The objective of modelling from data is not that the model simply fits the training data well. Rather, the goodness of a model is characterized by its generalization capability, interpretability and ease for knowledge extraction.
Sheng Chen, Chen, Sheng
core  

Development of a new meshless — point weighted least-squares (PWLS) method for computational mechanics [PDF]

open access: yes, 2004
A truly meshless approach, point weighted least-squares (PWLS) method, is developed in this paper. In the present PWLS method, two sets of distributed points are adopted, i.e. fields node and collocation point.
Li, Hua, Wang, Q. X., Lam, K. Y.
core   +1 more source

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