Results 91 to 100 of about 3,586,130 (307)
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source
Sick leave among home-care personnel: a longitudinal study of risk factors
BMC Musculoskeletal Disorders, 2004 Background Sick leave due to neck, shoulder and back disorders (NSBD) is higher among health-care workers, especially nursing aides/assistant nurses, compared with employees in other occupations.
Holmström Eva B +3 more
doaj +1 more source
Maternal Labor Market Return, Parental Leave Policies, and Gender Inequality in Housework [PDF]
This study investigates how the duration of the work interruption and the labor market status of mothers upon their return affect the division of housework in couples after a birth.
Pia S. Schober
core
Paid Sick Days Access in the United States: Differences by Race/Ethnicity, Occupation, Earnings, and Work Schedule [PDF]
, 2014 Paid sick days bring substantial benefits to employers, workers, families, and communities. The economic and public health benefits of paid sick leave coverage include safer work environments; improved work life balance, reduced spread of contagion; and ...
Barbara Gault, Claudia Williams
core
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
The experiences of those on sick leave and their supervisors: exploratory focus group interviews
Fysioterapeuten, 2011 Aims: To explore the experiences of people on sick leave and their supervisors with regard to the handling of sick leave, cooperation with doctors and with The Norwegian Labour and Welfare Administration (NAV) in an Including work-life enterprise ...
Birte Barsnes +2 more
doaj
BMC Public Health, 2011 Background Although illness is an important cause of sick leave, it has also been suggested that non-medical risk factors may influence this association. If such factors impact on the period of decision making, they should be considered as triggers. Yet,
Lindholm Christina +6 more
doaj +1 more source
Putting the Horse Before the Cart: The Influence of Trigger Events on Justice Perceptions and Work Attitudes [PDF]
, 2017 To date very little research on organizational justice and work attitudes has focused on what starts the process that leads to these perceptions. A considerable amount of organizational research is focused on the end result (e.g., employees’ perceptions,
Cotton, John L., O\u27Neill, Bonnie S.
core +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source