Results 41 to 50 of about 4,306,090 (193)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
, 2020 Die Infobroschüre ist im Rahmen des partizipaitven Forschungsprojektes "Care Leaver erforschen Leaving Care" in Zusammenarbeit mit dem Care Leaver Netzwerk Region Basel entstanden.
Rein, Angela +9 more
core +1 more source
, 2021 Die Forschung zeigt, dass Transitionen im Leben ein gleichermassen subjektiv erfahrbares, alltagsweltlich eingebettetes wie auch institutionelle Regulierungen herausforderndes soziales Geschehen sind.
Gabriel, Thomas, Keller, Samuel
core +2 more sources
At Kibble we aim to help our most vulnerable young people go on to have fulfilling adult lives
Scottish Journal of Residential Child Care, 2018 This article outlines Kibble's early history as a reformatory school in Victorian times to the present context of Kibble Education and Care Centre's place in contemporary provision in children's services in Scotland.
Jim Gillespie
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Transition care for older people leaving hospital: 2005-06 to 2012-13 [PDF]
, 2014 Examines the outcomes for the 87,000 people who received care under the Transition Care Program from 2005–06 to 2012–13. Summary For many older people, a hospital stay can be accompanied by a decline in functioning.
core
A Phenomenological Approach to Care Leavers’ Transition to Higher Education [PDF]
, 2012 Previous research conducted in the UK has highlighted issues with the educational experiences of care leavers in general and has suggested that life transitions affect care leavers’ later experiences.
King, Nigel +2 more
core +1 more source
SUPPORT FOR YOUTH LEAVING CARE: A NATIONAL RESEARCH STUDY, INDIA
International Journal of Child, Youth & Family Studies, 2020 This paper is a condensed version of a study entitled “Beyond 18: Leaving Child Care Institutions — A Study of Aftercare Practices in Five States of India”, conducted and published in 2019 by Udayan Care, a charitable organisation, with support from ...
Kiran Modi +5 more
doaj +1 more source