Results 61 to 70 of about 4,646,916 (286)
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
The Dedication: Leaving Evidence of Life, Death, Care, and Confinement During COVID-19
, 2023 In 2020, the COVID-19 pandemic exploded and nursing homes rapidly became overwhelmed with disease, death, and despair. During this time, I learned Sylvia, an old woman with dementia I had befriended, was one of the many old and disabled people confined ...
Hailee M. Yoshizaki-Gibbons
core +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
, 2019 Ubergange aus der Heimerziehung oder aus Pflegefamilien ins Erwachsenenleben sind mit einer sehr einschneidenden Veranderung der Lebenssituation junger Menschen verbunden. Sobald die Fremdunterbringung nicht mehr besteht, ordnen sich auch die Rechtsverhaltnisse fur Care Leaver komplett neu.
Raabe, Benjamin, Thomas, Severine
openaire +2 more sources
Foster Carers’ Perspective on Financial Issues When Young People Leave Care
Social InclusionFoster care can be defined as a professional assignment that emphasises the importance of family‐like relationships. The paradox in foster care lies in the tension between the professional perspective, where remuneration is provided for the care given ...
Ingrid Höjer, Inger Oterholm
doaj +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Social Work and Society, 2014 The purpose of this study is to examine young care leavers’ narrative accounts expressed as turning points connected to their experiences of being in care and leaving care. Telephone interviews were conducted with 65 young people, between 18 and 26 years
Ingrid Höjer, Yvonne Sjöblom
doaj +2 more sources
Sociétés et Jeunesses en Difficulté, 2010 This article aims at understanding what becomes of young people leaving care, by examining the processes by which they enter adulthood, what obstacles they face, how they behave and how they understand their actions.
Martin Goyette, Marie-Noële Royer
doaj
FEBS Letters, EarlyView.Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source