Results 61 to 70 of about 4,306,090 (193)

Foster Carers’ Perspective on Financial Issues When Young People Leave Care

open access: yesSocial Inclusion
Foster care can be defined as a professional assignment that emphasises the importance of family‐like relationships. The paradox in foster care lies in the tension between the professional perspective, where remuneration is provided for the care given ...
Ingrid Höjer, Inger Oterholm
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

What Makes a Difference? Turning Points for Young People in the Process of Leaving Placements in Public Care.

open access: yesSocial Work and Society, 2014
The purpose of this study is to examine young care leavers’ narrative accounts expressed as turning points connected to their experiences of being in care and leaving care. Telephone interviews were conducted with 65 young people, between 18 and 26 years
Ingrid Höjer, Yvonne Sjöblom
doaj   +2 more sources

Interdépendance des transitions vers l’autonomie de jeunes ayant connu un placement : le rôle des soutiens dans les trajectoires d’insertion

open access: yesSociétés et Jeunesses en Difficulté, 2010
This article aims at understanding what becomes of young people leaving care, by examining the processes by which they enter adulthood, what obstacles they face, how they behave and how they understand their actions.
Martin Goyette, Marie-Noële Royer
doaj  

PREPAREDNESS FOR EMANCIPATION OF YOUTH LEAVING ALTERNATIVE CARE IN SERBIA

open access: yesInternational Journal of Child, Youth & Family Studies, 2018
The process of preparing young people for leaving alternative care is not sufficiently researched in Serbia. In order to define what support is necessary for their successful emancipation, this study of 150 young people in care aims to analyse both their
Anita Burgund Isakov, Jasna Hrnčić
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Einblicke ins partizipative Forschungs- und Entwicklungsprojekt «Care Leaver erforschen Leaving Care»

open access: yes, 2018
Als ‚Care Leaver‘ werden junge Menschen bezeichnet, die in der stationären Jugendhilfe oder einer Pflegefamilie gelebt haben und sich im Übergang ins Erwachsenenalter befinden.
Rein, Angela   +2 more
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Strukturelle Rahmung der Statuspassage „Leaving Care“. Auswirkungen auf Bildungs- und Erwerbseintrittsprozesse aus Struktur- und Subjektperspektive

open access: yes, 2018
Internationale Studien verweisen darauf, dass Care Leaver im Vergleich zu Peers die Schule oder die Berufsbildung häufiger mit einem tieferen oder keinem Abschluss verlassen, sie erreichen selten einen tertiären Bildungsabschluss, sind häufiger ...
Schaffner, Dorothee
core  

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