Results 61 to 70 of about 389,900 (297)

SUPPORT FOR YOUTH LEAVING CARE: A NATIONAL RESEARCH STUDY, INDIA

open access: yesInternational Journal of Child, Youth & Family Studies, 2020
This paper is a condensed version of a study entitled “Beyond 18: Leaving Child Care Institutions — A Study of Aftercare Practices in Five States of India”, conducted and published in 2019 by Udayan Care, a charitable organisation, with support from ...
Kiran Modi   +5 more
doaj   +1 more source

Handreichung Leaving Care

open access: yes, 2019
Ubergange aus der Heimerziehung oder aus Pflegefamilien ins Erwachsenenleben sind mit einer sehr einschneidenden Veranderung der Lebenssituation junger Menschen verbunden. Sobald die Fremdunterbringung nicht mehr besteht, ordnen sich auch die Rechtsverhaltnisse fur Care Leaver komplett neu.
Raabe, Benjamin, Thomas, Severine
openaire   +2 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Family factors in early school leaving [PDF]

open access: yes, 2013
Young people who leave school early are at greater risk of experiencing long-term unemployment and slipping into social exclusion as a result. This paper looks at the risk factors associated with young people exiting the education system prematurely,
Elly Robinson, Veronica Meredith
core  

Leaving Care: Unaccompanied Asylum- Seeking Young Afghans Facing Return

open access: yesRefuge, 2015
Unaccompanied asylum-seeking children in the United Kingdom approach adulthood knowing that they will be encouraged or even forced to return to their countries of birth.
Kim Robinson, Lucy Williams
doaj   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Leaving Care in the UK and Scandinavia:Is It All That Different in Contrasting Welfare Regimes? [PDF]

open access: yes, 2016
In both the UK and Scandinavia, young people leaving care have traditionally experienced accelerated and compressed transition pathways, without access to the levels of practical, financial and emotional support that are typically available to their ...
Katie Hollingworth   +13 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Assessing outcomes : a social psychological interpretation of life course trajectories for young people leaving care [PDF]

open access: yes
This study explores the experiences of young people who have been 'looked after' during the transitional period in which they leave 'care', moving on to live independently.
Horrocks, Christine
core  

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