Results 11 to 20 of about 431,916 (392)

A Useful Guide to Lectin Binding: Machine-Learning Directed Annotation of 57 Unique Lectin Specificities

bioRxiv, 2021
Glycans are critical to every facet of biology and medicine, from viral infections to embryogenesis. Tools to study glycans are rapidly evolving, however the majority of our knowledge is deeply dependent on binding by glycan binding proteins (e.g ...
Daniel Bojar, Lawrence Meche, Guanmin Meng, William S. Eng, David F. Smith, R. Cummings, L. Mahal   +6 more
semanticscholar   +1 more source

35 years in plant lectin research: a journey from basic science to applications in agriculture and medicine

Glycoconjugate Journal, 2021
Plants contain an extended group of lectins differing from each other in their molecular structures, biochemical properties and carbohydrate-binding specificities.
E. V. Van Damme
semanticscholar   +1 more source

130 years of Plant Lectin Research

Glycoconjugate Journal, 2020
Lectins are proteins with diverse molecular structures that share the ability to recognize and bind specifically and reversibly to carbohydrate structures without changing the carbohydrate moiety.
Mariya Tsaneva, E. V. Van Damme
semanticscholar   +1 more source

Application of Lectin Microarrays for Biomarker Discovery

ChemistryOpen, 2020
Many proteins in living organisms are glycosylated. As their glycan patterns exhibit protein‐, cell‐, and tissue‐specific heterogeneity, changes in the glycosylation levels could serve as useful indicators of various pathological and physiological states.
K. Dang, Wenjuan Zhang, Shanfeng Jiang, Xiao Lin, A. Qian   +4 more
semanticscholar   +1 more source

Glycan-Gold Nanoparticles as Multifunctional Probes for Multivalent Lectin-Carbohydrate Binding: Implications for Blocking Virus Infection and Nanoparticle Assembly.

Journal of the American Chemical Society, 2020
Multivalent lectin-glycan interactions are widespread in biology and are often exploited by pathogens to bind and infect host cells. Glycoconjugates can block such interactions and thereby prevent infection.
Darshita Budhadev, E. Poole, I. Nehlmeier, Yuanyuan Liu, J. Hooper, Elizabeth Kalverda, Uchangi Satyaprasad Akshath, N. Hondow, W. Turnbull, S. Pöhlmann, Yuan Guo, Dejian Zhou   +11 more
semanticscholar   +1 more source

Alginate Modification and Lectin-Conjugation Approach to Synthesize the Mucoadhesive Matrix

Applied Sciences, 2021
Alginates are natural anionic polyelectrolytes investigated in various biomedical applications, such as drug delivery, tissue engineering, and 3D bioprinting. Functionalization of alginates is one possible way to provide a broad range of requirements for
Arlina Prima Putri, Francesco Picchioni, Sri Harjanto, Mochamad Chalid   +3 more
doaj   +1 more source

Endogenous mammalian lectin localized extracellularly in lung elastic fibers. [PDF]

, 1984
An affinity-purified antibody preparation raised against a beta-galactoside-binding lectin from bovine lung was used to localize a similar lectin in rat lung by immunofluorescence and by electron microscopy after on-grid staining visualized with ...
Barondes, SH, Cerra, RF, Haywood-Reid, PL   +2 more
core   +3 more sources

Gene Expression Profiling of Bronchoalveolar Lavage Cells Preceding a Clinical Diagnosis of Chronic Lung Allograft Dysfunction. [PDF]

, 2017
BackgroundChronic Lung Allograft Dysfunction (CLAD) is the main limitation to long-term survival after lung transplantation. Although CLAD is usually not responsive to treatment, earlier identification may improve treatment prospects.MethodsIn a nested ...
Ardehali, Abbas, Belperio, John A, Birjandi, Shirin, DerHovanessian, Ariss, Elashoff, David, Gregson, Aric L, Lynch, Joseph P, Palchevskiy, Vyacheslav, Palmer, Scott M, Patel, Naman, Ross, David J, Saggar, Rajan, Sayah, David M, Shino, Michael Y, Wang, Xiaoyan, Weigt, S Samuel   +15 more
core   +6 more sources

Synthesis of β-d-galactopyranoside-Presenting Glycoclusters, Investigation of Their Interactions with Pseudomonas aeruginosa Lectin A (PA-IL) and Evaluation of Their Anti-Adhesion Potential

Biomolecules, 2019
Pseudomonas aeruginosa is an opportunistic human pathogen associated with cystic fibrosis. This bacterium produces, among other virulence factors, a soluble d-galactose-specific lectin PA-IL (LecA).
Lenka Malinovská, Son Thai Le, Mihály Herczeg, Michaela Vašková, Josef Houser, Eva Fujdiarová, Jan Komárek, Petr Hodek, Anikó Borbás, Michaela Wimmerová, Magdolna Csávás   +10 more
doaj   +1 more source

Optimisation of the enzyme-linked lectin assay for enhanced glycoprotein and glycoconjugate analysis [PDF]

, 2011
Lectin’s are proteins capable of recognising and binding to specific oligosaccharide tructures found on glycoproteins and other biomoloecules. As such they have found tility for glycoanalytical applications.
Afrough, Aileen Creavin, Ambrosi, Andrews, Brendan O’Connor, Campbell, Charlwood, Chen, Debray, Drickamer, Duk, Dwek, Eisen, Geyer, Guile, Harvey, Hsu, Huber, Iskratsch, Jiménez-Barbero, Karamanska, Karlsson, Kim, Kirkeby, Kristiansen, Laemmli, Lis, Loris, Michael O’Connell, North, Olausson, Paul Clarke, Pilobello, Pilobello, Raman, Roisin Thompson, Rosenfeld, Royle, Rudd, Rudd, Rudd, Sparbier, Studentsov, Trimble, Varki, Wu, Wu, Wu, Wu   +48 more
core   +2 more sources