Synergistic inhibition of gastric cancer cell proliferation by concanavalin A and silibinin via attenuation of the JAK/STAT3 signaling pathway and molecular docking analysis [PDF]
HereditasBackground In the current period of pharmaceutical discovery, herbal remedies have shown to be an unmatched supply of anticancer medications. Plants and their derivatives, through analogues, play a vital role in cancer treatment.
Gaoyan Hua +3 more
doaj +2 more sources
Comparison of the oxidative respiratory burst and mitogen-induced leukocyte responses of camels, goats, sheep, and cows [PDF]
Veterinary World, 2022 Background and Aim: The reports from the Ministry of Agriculture and Fisheries suggest that camels suffer less compared to goats, sheep, and cows from a number of common infectious diseases in Oman.
Abeer Al-Hamrashdi +3 more
doaj +1 more source
Comparison of acute immunological liver injury models in two different species of mice [PDF]
Jichu yixue yu linchuang, 2023 Objective To explore the dose difference on concanavalin A (Con A) induced acute immunological injury of liver in two different species of mice. Methods Thirty six male BALB/C mice and 40 male C57BL/6 mice were randomly divided into 6 groups.BALB/C mice ...
HU Ning, HUANG Hannian, XIA Daozong
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Differences in the signaling pathways of α1A- and α1B-adrenoceptors are related to different endosomal targeting [PDF]
, 2013 Aims: To compare the constitutive and agonist-dependent endosomal trafficking of α1A- and α1B-adrenoceptors (ARs) and to establish if the internalization pattern determines the signaling pathways of each subtype.
A Hirasawa +54 more
core +10 more sources
Concanavalin A-induced autoimmune hepatitis model in mice: Mechanisms and future outlook
Open Life Sciences, 2022 The concanavalin A (Con A)-induced liver injury mouse model is a typical animal model focusing on T cell-dependent hepatic damage in the field of autoimmune hepatitis (AIH).
Liu Yang, Hao Huiqin, Hou Tiezheng
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Cellular and Molecular Gastroenterology and Hepatology, 2021 Background & Aims: Aberrant lymphocyte homing could potentially link inflammatory processes in the intestine and the liver, as distinct hepatobiliary diseases frequently develop as extra-intestinal manifestations in inflammatory bowel disease.
Angela Schippers +10 more
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Медицинская иммунология, 2023 As is known, bacterial polyamines, which include cadaverine and putrescine, are capable of influencing the activity of immunocompetent cells in many ways.
А. Р. Godovalov, I. А. Morozov
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The carbon reactions of photosynthesis: role of lectins and glycoregulation
Photosynthetica, 2020 Modulation of glycoregulation in agriculture is reviewed here with emphasis on the elucidation of previously unknown pathways involving vacuolar lectins as well as a bypass of lectins that direct free sugars toward productivity.
A.M. NONOMURA +4 more
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Structural Arrangement Produced by Concanavalin A Binding to Homomeric GluK2 Receptors
Membranes, 2021 Kainate receptors are members of the ionotropic glutamate receptor family. They form cation-specific transmembrane channels upon binding glutamate that desensitize in the continued presence of agonists.
Cuauhtemoc U. Gonzalez +3 more
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Inhibitory effect of liposomal quercetin on acute hepatitis and hepatic fibrosis induced by concanavalin A [PDF]
Brazilian Journal of Medical and Biological Research, 2014 Immune response plays an important role in the development of hepatic fibrosis. In the present study, we investigated the effects of quercetin on hepatitis and hepatic fibrosis induced by immunological mechanism.
Y. Wan +5 more
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