Results 31 to 40 of about 118,548,475 (188)

Recognition of Concanavalin A by Cationic Glucosylated Liposomes

open access: yes, 2014
Recognition of Concanavalin A by Cationic Glucosylated ...
Antonio Martino   +24 more
core   +1 more source

New Activity of a Protein from Canavalia ensiformis

open access: yesScientia Pharmaceutica, 2014
Concanavalin A is a legume lectin which preferentially agglutinates transformed cells and shows antitumor effects on human breast carcinoma cells in vitro and in vivo.
Vanya Petkova BOGOEVA   +2 more
doaj   +1 more source

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

open access: yesAdvanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang   +10 more
wiley   +1 more source

Longitudinal Plasmonic Detection of Glucose Using Gold Nanorods

open access: yesNanomaterials and Nanotechnology, 2014
Gold nanorod-based affinity sensors were developed utilizing concanavalin-A/dextran/glucose chemistry to detect glucose. The gold nanorods, synthesized using the seed-mediated method, were first coated with dextran sulfate.
Ching-An Peng, Sushil Pachpinde
doaj   +1 more source

Glucocorticoid Receptor Signaling in Myeloid Cells Orchestrates Inflammation Resolution and Muscle Repair

open access: yesAdvanced Science, EarlyView.
Glucocorticoids (GC) are widely used to reduce inflammation. We show that the glucocorticoid receptor in myeloid cells regulates macrophage cell cycle and genome integrity during muscle regeneration. We demonstrate that dexamethasone administration during the early inflammatory phase delays muscle repair by increasing macrophage proliferation ...
Sirine Souali‐Crespo   +11 more
wiley   +1 more source

Nuclear IDH3A Drives Transcriptional Programs in Melanoma via the YBX1–JUN/FOS Axis

open access: yesAdvanced Science, EarlyView.
Genomic amplification drives aberrant nuclear localization of IDH3A in melanoma. Independent of its canonical metabolic activity, nuclear IDH3A cooperates with YBX1 to activate the c‐JUN/c‐FOS transcriptional program, while NONO facilitates its nuclear localization.
Juan Ran   +10 more
wiley   +1 more source

Interaction between Concanavalin A and brain lysosomal acid hydrolases

open access: yes, 1974
All the five sheep brain lysosomal acid hydrolases tested, namely arylsulphatase A, acid phosphatase, β-N-acetylhexosaminidase, β-galactosidase and β-glucuronidase bind with Concanavalin A and form enzymatically active precipitate.
Bishayee, Subal, Bachhawat, B. K.
core   +1 more source

An "extension" of the carbohydrate binding specificity of concanavalin A [PDF]

open access: yes, 1973
Evidence based on the quantitative precipitin method and hapten inhibition technique demonstrates that concanavalin A may interact with internal 2-O-linked [alpha]--mannopyranosyl residues as may occur in glycoproteins and polysaccharides.Peer ...
Goldstein, Irwin J.   +3 more
core   +1 more source

Aspirin‐Derived Salicyl‐CoA Drives Histone Lysine Salicylation Regulated by CBP and SIRT2

open access: yesAdvanced Science, EarlyView.
Aspirin‐derived salicyl‐CoA serves as a previously unrecognized acyl donor for protein lysine salicylation. This study identifies histone lysine salicylation as a reversible epigenetic modification regulated by CBP and SIRT2, expanding the biochemical actions of aspirin beyond its canonical acetylation‐dependent mechanisms and providing a new framework
Facai Zhang   +15 more
wiley   +1 more source

Fermented Lentinus edodes extract containing α-glucan ameliorates concanavalin A-induced autoimmune hepatitis in mice

open access: yesFood Science and Human Wellness
Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease that threatens human health worldwide. The aim of this study was to detect the protective effect of a fermented Lentinus edodes extract containing α-glucan (FLA), in a concanavalin A ...
Xin Hu   +5 more
doaj   +1 more source

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