Results 41 to 50 of about 345,151 (401)
Detection of inflammation- and neoplasia-associated alterations in human large intestine using plant/invertebrate lectins, galectin-1 and neoglycoproteins [PDF]
, 1998 Commonly, plant and invertebrate lectins are accepted glycohistochemical tools for the analysis of normal and altered structures of glycans in histology and pathology.
Bosbach, R. +3 more
core +1 more source
Proteomes, 2015 Developing a urine test to detect bladder tumours with high sensitivity and specificity is a key goal in bladder cancer research. We hypothesised that bladder cancer-specific glycoproteins might fulfill this role.
Sarah R. Ambrose +8 more
doaj +1 more source
An algal lectin griffithsin inhibits Hantaan virus infection in vitro and in vivo
Frontiers in Cellular and Infection Microbiology, 2022 Hantaan virus (HTNV) is the etiological pathogen of hemorrhagic fever with renal syndrome in East Asia. There are currently no effective therapeutics approved for HTNV and other hantavirus infections.
Yajing Zhao +25 more
doaj +1 more source
Survival outcome and EMT suppression mediated by a lectin domain interaction of Endo180 and CD147 [PDF]
, 2014 Epithelial cell-cell contacts maintain normal glandular tissue homeostasis, and their breakage can trigger epithelial-to-mesenchymal transition (EMT), a fundamental step in the development of metastatic cancer.
Darby, Steven +8 more
core +2 more sources
Lectin domains at the frontiers of plant defense
Frontiers in Plant Science, 2014 Plants are under constant attack from pathogens and herbivorous insects. To protect and defend themselves, plants evolved a multi-layered surveillance system, known as the innate immune system.
Nausicaä Lannoo, E. V. Van Damme
semanticscholar +1 more source
PROTEOMICS – Clinical Applications, 2009 AbstractLectin microarray is a new technology that utilizes a panel of lectins immobilized on well‐defined substrate for high‐throughout analysis of glycans and glycoproteins. In this article, we have reviewed the fabrication and detection schemes in lectin microarray and discussed its novel applications in glycomics. We have also demonstrated a lectin
Shen, Hu, David T, Wong
openaire +2 more sources
Signaling by myeloid C-type lectin receptors in immunity and homeostasis.
Annual Review of Immunology, 2012 Myeloid cells are key drivers of physiological responses to pathogen invasion or tissue damage. Members of the C-type lectin receptor (CLR) family stand out among the specialized receptors utilized by myeloid cells to orchestrate these responses.
D. Sancho, C. Reis e Sousa
semanticscholar +1 more source
Marine Drugs, 2015 Plant lectins have attracted much attention for biomedical applications including targeted drug delivery system and therapy against tumors and microbial infections.
Jong Won Han +5 more
doaj +1 more source
Pharmaceutics, 2023 Type I fimbriae are the main adhesive organelles of uropathogenic Escherichia coli (UPEC), consisting of four different subunits. Their component with the most important role in establishing bacterial infections is the FimH adhesin located at the ...
Georgia I. Nasi +6 more
doaj +1 more source
Mannose binding lectin is required for alphavirus-induced arthritis/myositis [PDF]
, 2015 Mosquito-borne alphaviruses such as chikungunya virus and Ross River virus (RRV) are emerging pathogens capable of causing large-scale epidemics of virus-induced arthritis and myositis.
Blevins, Lance K. +10 more
core +1 more source