Results 31 to 40 of about 3,190,451 (315)
Lectins and traffic in the secretory pathway [PDF]
Evidence is accumulating that intracellular animal lectins play important roles in quality control and glycoprotein sorting along the secretory pathway. Calnexin and calreticulin in conjunction with associated chaperones promote correct folding and oligomerization of many glycoproteins in the endoplasmic reticulum (ER).
Hauri, H. +3 more
openaire +4 more sources
Inactivation of the Complement Lectin Pathway by Candida tropicalis Secreted Aspartyl Protease-1.
Candida tropicalisis an opportunistic fungal pathogen and is one of the most frequently isolated non-albicans species. It can cause localised as well as invasive systemic infections particularly in immunocompromised patients.
Nisha Valand +9 more
semanticscholar +1 more source
The complement system is the most ancient components in the innate immunity, mainly functioning to primarily eliminate bacterial agents intravascularly.
Marina V. Smolnikova +1 more
doaj +1 more source
Vacuolar ATPase depletion contributes to dysregulation of endocytosis in bloodstream forms of Trypanosoma brucei [PDF]
BACKGROUND Vacuolar H-ATPase (V-ATPase) is a highly conserved protein complex which hydrolyzes ATP and pumps protons to acidify vacuolar vesicles.
Hide, G +4 more
core +2 more sources
Overexpression of Nictaba-like lectin genes from glycine max confers tolerance towards Pseudomonas syringae infection, aphid infestation and salt stress in transgenic Arabidopsis plants [PDF]
Plants have evolved a sophisticated immune system that allows them to recognize invading pathogens by specialized receptors. Carbohydrate-binding proteins or lectins are part of this immune system and especially the lectins that reside in the ...
Smagghe, Guy +2 more
core +6 more sources
Use of C4d as a diagnostic tool to classify membranoproliferative glomerulonephritis
Background: Membranoproliferative glomerulonephritis (MPGN type I, II and III) was reclassified in 2013 as MPGN and C3 glomerulopathy (C3G) based on the complement system activation mechanism.
Nirupama Gupta +3 more
doaj +3 more sources
Traditionally, determination of inhibitory potency of complement inhibitors is performed by the hemolytic assay. However, this assay is not applicable to the lectin pathway, thus impeding the understanding of complement inhibitors against the overall ...
Mulu Wu +3 more
doaj +1 more source
Mannose-binding lectin 2 gene and risk of adult glioma. [PDF]
The immune system is likely to play a key role in the etiology of gliomas. Genetic polymorphisms in the mannose-binding lectin gene, a key activator in the lectin complement pathway, have been associated with risk of several cancers.To examine the role ...
Dominique S Michaud +12 more
doaj +1 more source
Paths reunited: initiation of the classical and lectin pathways of complement activation [PDF]
Understanding the structural organisation and mode of action of the initiating complex of the classical pathway of complement activation (C1) has been a central goal in complement biology since its isolation almost 50 years ago.
Keeble, Anthony H. +4 more
core +1 more source

