Results 301 to 310 of about 193,445 (333)

Tumor glyco-immunology, glyco-immune checkpoints and immunotherapy. [PDF]

J Immunother Cancer
Pinho SS, Macauley MS, Läubli H.
europepmc   +1 more source

Nanomedicine for Oral Delivery: Strategies to Overcome the Biological Barriers

Small Methods, EarlyView.
Oral delivery is a preferred administration route for many clinical applications, valued for its strong patient compliance. In this review, how nanoparticles are engineered and deployed to overcome the gastrointestinal barriers that impede clinical translation of oral delivery formulations is examined.
Luke J. Kubiatowicz, Nima Pourafzal, Audrey T. Zhu, Zhongyuan Guo, Ronnie H. Fang, Liangfang Zhang   +5 more
wiley   +1 more source

Evaluation of Integrin Glycovariants as Biomarkers of Metastasis, Invasion, and Therapy Stratification in Head and Neck Squamous Cell Carcinoma. [PDF]

Cancer Med
Routila E, Salminen S, Mahran R, Toriseva M, Irjala H, Haapio E, Kytö E, Ventelä S, Pettersson K, Routila J, Gidwani K, Leivo J.   +11 more
europepmc   +1 more source

Synthesis of Boronic Acid‐Functionalized Core–Shell Mesoporous Silica–TiO2 Nanocomposite for Specific Enrichment of Glycopeptides From Biological Samples

Small Methods, EarlyView.
The schematic illustrates a workflow showing the current investigation using a boronic acid‐functionalized core–shell mesoporous silica‐TiO₂ (CSMS@TiO₂‐GLYMO‐APB) for N‐glycopeptide enrichment from biological samples, involving trypsin digestion, enrichment, deglycosylation with PNGase F, and subsequent mass spectrometry (MALDI‐TOF MS and Nano‐LC‐MS/MS)
Mohamed Adly Gab‐Allah, Maryam Adelipour, Hyojin Hwang, Reham M. Marzouk, Heejin Lim, Jooyeon Oh, Ji‐Hyun Cha, Jaebeom Lee, Jeongkwon Kim   +8 more
wiley   +1 more source

Sweet Aging: Glycocalyx and Galectins in CNS Aging and Neurodegenerative Disorders. [PDF]

Int J Mol Sci
Mir MY, Legradi A.
europepmc   +1 more source

Cascade Ultrasonic Cavitation Enables Microbubble–Nanoparticle Hybrid to Broadly Accumulate and Penetrate into Pancreatic Ductal Adenocarcinoma

Small Structures, EarlyView.
A novel cascade twice ultrasonic cavitation strategy utilizing macrophage membrane‐modified microbubble‐nanoparticle hybrid (MMB@TFHPD) is engineered to enhance drug delivery efficiency in pancreatic ductal adenocarcinoma. The system implements sequential ultrasound applications: initially disrupting the blood–tumor barrier, followed by triggering deep
Dequan Ye, Guowei Wang, Xiao Liu, Yijie Chen, Jifan Chen, Hua Yin, Yuhan Fu, Fei Gao, Lina Tang, Pintong Huang   +9 more
wiley   +1 more source

Tepary Bean (<i>Phaseolus acutifolius</i>) Lectins as Modulators of Intracellular Calcium Mobilization in Breast Cancer and Normal Breast Cells. [PDF]

Int J Mol Sci
Díaz-Betancourt A, Galicia-Castillo ME, Morales-Tlalpan V, Chávez-Servín JL, Blanco-Labra A, García-Gasca T, Saldaña C.   +6 more
europepmc   +1 more source

Cadmium‐Induced Mitochondrial and MAMs Dysregulation in Rat Testis: The Protective Role of D‐Aspartate

Environmental Toxicology, EarlyView.
ABSTRACT Cadmium (Cd), a heavy metal, disrupts the structure of seminiferous tubules and induces cell death at multiple stages of sperm development. Cd also impairs Leydig cells (LCs), resulting in reduced serum testosterone (T) levels. This study primarily examined the impact of Cd on the mitochondrial compartment and mitochondrial‐associated ...
Debora Latino, Sara Falvo, Massimo Venditti, Alessandra Santillo, Giulia Grillo, Gabriella Chieffi Baccari, Imed Messaoudi, Maria Maddalena Di Fiore   +7 more
wiley   +1 more source

Arbovirus suppression of a lectin protein-mediated broad-spectrum resistance enhances herbivorous vector performance and viral transmission. [PDF]

Nat Commun
Yang Z, Wu W, Xu Z, Li Y, Zhang H, Li L, Chen J, Sun B, Sun Z.   +8 more
europepmc   +1 more source

In-situ profiling of glycosylation on single cells with surface plasmon resonance imaging. [PDF]

Nat Commun
Liu X, Ma J, Zhang Y, Xu Y, Wang Y, Yang D, Wang D, Liu Q, Zhang F.   +8 more
europepmc   +1 more source