Results 81 to 90 of about 75,424 (310)

Decoding a Gut Commensal Signal: Structural and Immunological Profiling of Segatella Copri Lipopolysaccharide

open access: yesAngewandte Chemie, EarlyView.
The lipopolysaccharide (LPS) of Segatella copri is a structurally unique, immunomodulatory glycoconjugate. Combining mass spectrometry (MS), nuclear magnetic resonance (NMR), and cytometry by time‐of‐flight (CyTOF), we uncover a rough‐type LPS with reduced TLR4 agonism and selective monocyte effects, further highlighting the key role of LPS chemistry ...
Luca De Simone Carone   +17 more
wiley   +2 more sources

From inflammation to immune regulation: The dual nature of dietary lectins in health and disease

open access: yesHeliyon
Beans, vegetables, fruits, and mushrooms offer a delightful array of fragrances and an abundance of nutrients, including essential vitamins, minerals, protein rich in vital amino acids, and omega-3 fatty acids.
Emadeldin H.E. Konozy   +1 more
doaj   +1 more source

Use of lectins in immunohematology

open access: yesAsian Journal of Transfusion Science, 2016
Lectins are carbohydrate binding proteins present in seeds of many plants, especially corals and beans, in fungi and bacteria, and in animals. Apart from their hemagglutinating property, a wide range of functions have been attributed to them. Their importance in the area of immunohematology is immense. They are used to detect specific red cell antigens,
Kanjaksha Ghosh, Ajit Gorakshakar
openaire   +4 more sources

Enhanced Single‐Particle Upconversion Imaging via Energy Migration Boosting

open access: yesAdvanced Science, EarlyView.
A core‐shell‐shell Yb3⁺/Er3⁺ UCNP architecture is engineered to balance energy migration and back energy transfer, yielding more than a tenfold enhancement in single‐particle brightness. Leveraging these optimized probes, it achieves long‐term, high‐resolution single‐particle tracking in live neurons, uncovering coordinated transport mechanisms of ...
Yanxin Zhang   +7 more
wiley   +1 more source

MUC15 Ectodomain Architecture Regulates Integrin Clustering to Control Cancer Metastasis

open access: yesAdvanced Science, EarlyView.
This study uncovers a size‐dependent adhesion paradigm, demonstrating that the glycocalyx protein MUC15 suppresses pancreatic cancer progression by attenuating integrin activation, focal adhesion assembly, and YAP mechanotransduction. Integrating computational modeling and experimental validation, the work reveals a mechanical mechanism by which MUC15 ...
Simei Zhang   +18 more
wiley   +1 more source

Isolation and Molecular Characterization of Two Lectins from Dwarf Elder (Sambucus ebulus L.) Blossoms Related to the Sam n1 Allergen

open access: yesToxins, 2013
Sambucus species contain a number of lectins with and without antiribosomal activity. Here, we show that dwarf elder (Sambucus ebulus L.) blossoms express two D-galactose-binding lectins that were isolated and purified by affinity chromatography and gel ...
Tomas Girbes   +5 more
doaj   +1 more source

Nanoscopic Mapping of the Extracellular Space in Amyloid Plaque‐rich Cortex

open access: yesAdvanced Science, EarlyView.
The extracellular space and diffusion around amyloid plaques are examined using shadow imaging and single‐particle tracking. Increased diffusivity is found near plaques, extracellular matrix alterations, and plaque core penetrability that varies with amyloid phenotype.
Juan Estaún‐Panzano   +11 more
wiley   +1 more source

Quantitative Study of the Combination of Lima Bean Lectin with Human Erythrocytes [PDF]

open access: bronze, 1962
William C. Boyd   +3 more
openalex   +1 more source

Diazine Endo‐Functionalized Tetraphenylethylene‐Based Cyclo[6]arenes for Molecular Recognition in Both Solution and Aggregate States

open access: yesAggregate, EarlyView.
To overcome poor molecular recognition in dilute solutions of tetraphenylethylene‐embedded cyclo[6]arenes, three macrocycles with functionalized cavities featuring diazine groups as endo‐binding sites are synthesized. Their recognition affinity continuously improves with increasing hydrogen‐bond acceptance of diazine groups.
Nan Pan   +6 more
wiley   +1 more source

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