Results 111 to 120 of about 9,672 (236)

Safety and efficacy of ledipasvir/sofosbuvir for the treatment of genotype 1 hepatitis C in subjects aged 65 years or older [PDF]

open access: bronze, 2015
Sammy Saab   +11 more
openalex   +1 more source

An Increase in the Prevalence of Clinically Relevant Resistance-Associated Substitutions in Four Direct-Acting Antiviral Regimens: A Study Using GenBank HCV Sequences

open access: yesPathogens
Direct-acting antivirals (DAAs) revolutionized the therapeutics of chronic hepatitis C. The emergence and transmission of HCV variants with resistance-associated substitutions (RASs) can undermine HCV treatment.
Roaa Khalil   +3 more
doaj   +1 more source

Effectiveness and safety of sofosbuvir/ledipasvir ± ribavirin treatment in liver and/or renal transplant patients with chronic hepatitis C: A single-center experience

open access: yesSAGE Open Medicine, 2018
Objective: Successful treatment is possible with novel direct-acting oral antiviral agents in solid organ transplant patients with hepatitis C. In this study, the effectiveness and safety of sofosbuvir/ledipasvir ± ribavirin treatment in liver and/or ...
Mete Akin   +5 more
doaj   +1 more source

Impact of a treatment as prevention strategy on hepatitis C virus transmission and on morbidity in people who inject drugs [PDF]

open access: yes, 2015
Background: Highly effective direct-acting antiviral (DAA) regimens (90% efficacy) are becoming available for hepatitis C virus (HCV) treatment. This therapeutic revolution leads us to consider possibility of eradicating the virus.
Cousien, Anthony   +5 more
core   +3 more sources

Concomitant Treatment of Hepatitis C Virus and Diffuse Large B-Cell Lymphoma with Direct-Acting Antivirals in HIV Coinfection: A Case Report

open access: yesJournal of the International Association of Providers of AIDS Care, 2019
This report describes a case of concomitant treatment of advanced diffuse large B-cell lymphoma with chemoimmunotherapy along with direct-acting antivirals for hepatitis C virus in a patient coinfected with HIV.
Alyssa Gallipani PharmD, BCACP   +3 more
doaj   +1 more source

Prediction of binding of FDA approved drug Ledipasvir to SARS-CoV2 mutants: an in silico study [PDF]

open access: green, 2021
Sheemona Chowdhary   +3 more
openalex   +1 more source

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