Results 81 to 90 of about 5,803 (182)

DEVELOPMENT AND VALIDATION OF STABILITY INDICATING RP-HPLC METHOD FOR SIMULTANEOUS ESTIMATION OF SOFOSBUVIR AND LEDIPASVIR IN TABLET DOSAGE FORM [PDF]

open access: yes, 2018
Simple, specific, accurate and precise reversed phase high pressure liquid chromatographic method has been developed for the simultaneous determination of Sofosbuvir and Ledipasvir in tablet dosage form by reversed phase C18 column (Kromasil C18 5μ, 250 ...
M.Prasanthi Evangelin*, S.Manohar Babu, Konda Ravi Kumar
core   +1 more source

Cost-effectiveness analysis of treatment timing considering the future entry of lower-cost generics for hepatitis C

open access: yesClinicoEconomics and Outcomes Research, 2018
Katherine Heath1,2 1Mathematical Ecology Research Group, Department of Zoology, University of Oxford, Oxford OX1 3PS, UK; 2New College, Oxford OX1 3BN, UK Background: Cost-benefit analyses are crucial to inform treatment policies, particularly when the ...
Heath K
doaj  

Persistence of Virologic Response after Liver Transplant in Hepatitis C Patients Treated with Ledipasvir / Sofosbuvir Plus Ribavirin Pretransplant

open access: yesAnnals of Hepatology, 2017
Introduction: Recurrence of HCV infection in patients with chronic hepatitis C virus (HCV) at the time of liver transplantation is nearly universal and reduces the likelihood of graft and patient survival.
Eric M. Yoshida   +19 more
doaj   +1 more source

Simultaneous estimation of ledipasvir and sofosbuvir in bulk and its dosage forms by stability indicating RP-HPLC method

open access: yes, 2019
The fixed-dose ledipasvir-sofosbuvir combination offers an effective and well-tolerated pill for the treatment of chronic hepatitis C infection. Only a few analytical works were carried out to estimate the Ledipasvir and Sofosbuvir drug combination in ...
Ismail, Yehea
core   +1 more source

Prices that make sofosbuvir/ledipasvir cost-effective, by four economic regions in China.

open access: yes, 2016
Prices that make sofosbuvir/ledipasvir cost-effective, by four economic regions in China.
Hui Zhuang (139189)   +34 more
core   +1 more source

Role of Direct Antiviral Agents in Treatment of Chronic Hepatitis C Infection in Renal Transplant Recipients

open access: yesJournal of Transplantation, 2018
Background. Since the introduction of direct antiviral agents (DAAs), morbidity of HCV has considerably decreased but still no guidelines have been formulated in renal transplant recipients (RTRs). We studied efficacy and tolerability of direct antiviral
Sourabh Sharma   +4 more
doaj   +1 more source

The baseline characteristics of the patients who were treated with sofosbuvir/ledipasvir (n = 493).

open access: yes, 2018
The baseline characteristics of the patients who were treated with sofosbuvir/ledipasvir (n = 493).
Takeshi Kure (5328974)   +16 more
core   +1 more source

Ledipasvir and Sofosbuvir Plus Ribavirin for Treatment of HCV Infection in Patients With Advanced Liver Disease [PDF]

open access: yes, 2015
Background & AimsThere are no effective and safe treatments for chronic hepatitis C virus (HCV) infection of patients who have advanced liver disease.MethodsIn this phase 2, open-label study, we assessed treatment with the NS5A inhibitor ledipasvir, the ...
Muir, Andrew J.   +64 more
core   +1 more source

Ledipasvir/sofosbuvir fixed-dose combination tablet in Taiwanese patients with chronic genotype 1 hepatitis C virus

open access: yes, 2017
Background and Aim:Pegylated-interferon-alpha plus ribavirin is the current standard-of-care regimen for treating chronic hepatitis C virus (HCV) infection in Taiwan; however, interferon-based regimens can be poorly tolerated.
Chuang, Wan-Long;Chien, Rong-Nan;Peng, Cheng-Yuan;Chang, Ting-Tsung;Lo, Gin-Ho;Sheen, I-Shyan;Wang, Horng-Yuan;Chen, Jyh-Jou;Yang, Jenny C.;Knox, Steven J.;Gao, Bing;Garrison, Kimberly L.;Mo, Hongmei;Pang, Phillip S.;Hsu, Yu-Chun;Hu, Tsung-Hui;Chu, Chi-Jen;Kao, Jia-Horng   +1 more
core   +1 more source

ICERs of sofosbuvir/ledipasvir compared to pegIFN plus RBV, by four economic regions in China.

open access: yes, 2016
ICERs of sofosbuvir/ledipasvir compared to pegIFN plus RBV, by four economic regions in China.
Hui Zhuang (139189)   +34 more
core   +1 more source

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