Results 61 to 70 of about 33,124 (331)

Percutaneous left atrial appendage occlusion: New perspectives for the method [PDF]

, 2017
Ischemic stroke is a common complication of atrial fibrillation (AF). Currently, oral anticoagulant drugs are the most commonly used method of stroke prevention. Left atrial appendage occlusion is thought to be the main source of thrombi in patients with
Gorczyca-Michta, Iwona, Wożakowska-Kapłon, Beata   +1 more
core   +2 more sources

Organ‐Specific and Conserved Regulatory Logic Orchestrates Gene Expression in the Embryonic Mesothelium

Advanced Science, EarlyView.
Integrated multi‐omic profiling maps the gene‐regulatory landscape of the coelomic mesothelium across heart, lung, and pancreas. A cardiac‐restricted regulatory program is uncovered in which TBX20 activates heart mesothelial (epicardial) cis‐regulatory elements, while MAF emerges as a conserved regulator of mesothelial identity.
Quang Minh Dang, Nicola Smart, Andia Nicole Redpath, Joaquim Miguel Vieira   +3 more
wiley   +1 more source

Left Atrial Appendage Closure –The WATCHMAN Device [PDF]

Current Cardiology Reviews, 2015
Atrial fibrillation (AF) is one of the most common arrhythmias seen in clinical cardiology practice. Patients with non-valvular AF have an approximately 5-fold increase in the risk of stroke, with an exponential increase with advancing age. Cardioembolic strokes carry a high mortality risk.
Akinapelli, Abhilash, Bansal, Ojas, Chen, Jack P., Pflugfelder, Alex, Gordon, Nicole, Stein, Kenneth, Huibregtse, Barbara, Hou, Dongming   +7 more
openaire   +2 more sources

Antithrombotic Therapy after Percutaneous Left Atrial Appendage Closure: Evidence, Challenges and Future Directions

Reviews in cardiovascular medicine, 2023
Percutaneous left atrial appendage closure (LAAC) has been established in clinical practice as an attractive alternative to oral anticoagulation for preventing stroke in patients with atrial fibrillation and high bleeding risk.
R. Galea, L. Räber
semanticscholar   +1 more source

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

Advanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang, Cancan Yao, Yan Chen, Ke Cai, Zhouping Lu, Boxuan Wu, Kun Yu, Yan Shi, Jianyuan Zhao, Xiangyu Zhou   +9 more
wiley   +1 more source

Discovering Interpretable Semantics from Radio Signals for Contactless Cardiac Monitoring

Advanced Science, EarlyView.
This study presents a semantic representation framework for clinically interpretable cardiac monitoring from contactless radio signals. It formulates radio semantic learning as an information‐bottleneck problem and approximates the objective via intra‐modal compression and cross‐modal alignment, structuring radio measurements into meaningful semantic ...
Jinbo Chen, Haoyu Wang, Guixin Xu, Yuqin Yuan, Xinmeng Cai, Zhengwu Wei, Dongheng Zhang, Qibin Sun, Tianwei Zhang, Cuntai Guan, Yan Chen   +10 more
wiley   +1 more source

Arterial hypotension during percutaneous procedures in the left atrial: It is not always pericardial tamponade!

Heart Vessels and Transplantation, 2022
On the stage of left atrial percutaneous procedures a number of acute complications and their management have been described. In the current brief report, coronary air embolism, its acute manifestations, differential diagnosis and outcomes were presented
Luis Antonio Arabia, Luis Aguinaga Arrascue   +1 more
doaj   +1 more source

Two-year clinical outcome from the Iberian registry patients after left atrial appendage closure [PDF]

, 2015
AIMS: The aim of this study was to observe the percentage of thromboembolic and haemorrhagic events over a 2-year follow-up in patients with non-valvular atrial fibrillation (NVAF) undergoing closure of the left atrial appendage (LAA) with an occlusion ...
Asensio, JM, Buendía, AB, Costa, MA, de Carlos, FG, Domínguez-Franco, A, Díaz, JA, Garibi, JH, González, IC, González, RM, Gragera, JE, Hernández, FH, López Mínguez, JR, Martín Yuste, V, Ribeiro, VG   +13 more
core   +1 more source

Shapley Additive Explanation for Local Class Differentiation: Local Explainability for Class Differentiation in Classification Models

Advanced Intelligent Systems, EarlyView.
An instance‐level, model‐agnostic explanation of class differentiation is introduced through SHAP‐LCD, linking probability shifts to feature‐wise Shapley contributions. The method operates on tabular and image data and is released in a fully reproducible implementation, offering a transparent way to examine, at each instance, why predictive models ...
Roxana M. Romero Luna, Hugo A. Ordoñez Erazo, Carlos A. Cobos Lozada   +2 more
wiley   +1 more source

Minitoracotomia axilar direita horizontal: opção estética e eficaz para correção de comunicação interventricular e interatrial em lactentes e crianças [PDF]

, 2014
Introduction:Congenital heart defects treatment shows progressive reduction in morbidity and mortality, however, the scar, resulting from ventricular (VSD) and atrial septal defect (ASD) repair, may cause discomfort.
Cascudo, Cybelle M, Castro, Rodrigo Moreira, Franchi, Sonia Meiken, Gomes, Walter José, Schreiber, Christian, Silva, José Pedro da, Silva, Luciana da Fonseca da, Turquetto, Aída Luiza Ribeiro   +7 more
core   +3 more sources