Results 101 to 110 of about 1,881,139 (280)

Jordan ideals and derivations in prime near-rings [PDF]

open access: yes, 2014
summary:In this paper we investigate $3$-prime near-rings with derivations satisfying certain differential identities on Jordan ideals, and we provide examples to show that the assumed restrictions cannot be ...
Raji, Abderrahmane   +2 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

On left $(\theta,\varphi)$-derivations of prime rings

open access: yes, 2005
summary:Let $R$ be a $2$-torsion free prime ring. Suppose that $\theta , \phi $ are automorphisms of $R$. In the present paper it is established that if $R$ admits a nonzero Jordan left $(\theta ,\theta )$-derivation, then $R$ is commutative. Further, as
Mohammad Ashraf, Ashraf, Mohammad
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

On centrally-extended left derivations in rings

open access: yesArabian Journal of Mathematics
AbstractWe aim to introduce the concept of centrally-extended left derivations and prove some related results to this new concept. The first part is devoted to prove that a centrally extended left derivation preserves the center of semiprime rings. The second part deals with equivalence between left derivations and our new concept.
Aziza Gouda, H. Nabiel
openaire   +1 more source

Three Vessel Coronary Cameral Fistulae Associated with New Onset Atrial Fibrillation and Angina Pectoris

open access: yesCase Reports in Vascular Medicine, 2014
Coronary cameral fistulas are abnormal communications between a coronary artery and a heart chamber or a great vessel which are reported in less than 0.1% of patients undergoing diagnostic coronary angiography.
Murat Yuksel   +5 more
doaj   +1 more source

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