Results 61 to 70 of about 2,394,289 (288)

Open Dislocation of Fifth Digit [PDF]

open access: yes, 2016
History of present illness: A 17-year-old female presented with a chief complaint of right fifth finger pain. The patient reported that she was playing volleyball when she blocked an opponent’s shot and sustained an injury to her right fifth finger ...
Rowe, Robert   +4 more
core   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

open access: yesFEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow   +12 more
wiley   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

open access: yesFEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima   +8 more
wiley   +1 more source

Joint reconstruction using sternocleidomastoid tendon autograft as a treatment for traumatic posterior dislocation of sternoclavicular joint: A case report

open access: yesTrauma Case Reports, 2018
Introduction: Posterior sternoclavicular joint dislocations are extremely rare and emergent injuries. Presentation of case: We presented a case of a seventeen-year-old male patient who was diagnosed with traumatic posterior dislocation.
Wahyu Widodo   +2 more
doaj   +1 more source

Agrammatic comprehension of contrastive focus and clitic left dislocation in Catalan

open access: yes, 2022
The dataset contains the raw scores of a group of healthy participants and subjects with agrammatic aphasia on two sentence-picture tasks that evaluated the comprehension of contrastive focus and clitic left dislocation in ...
Salmons Llussa, Io   +3 more
core   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

A rare case of an isolated scaphoid dislocation neglected for 45 years: A case report and literature review

open access: yesActa Orthopaedica et Traumatologica Turcica
Isolated dislocation of the scaphoid bone is an extremely rare injury. If left untreated, results may be catastrophic. This paper presents a late complication of a neglected open scaphoid dislocation injury.
Erdi İmre
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Grain size, size-distribution and dislocation structure from diffraction peak profile analysis [PDF]

open access: yes, 2002
Diffraction peak profile analysis (or Line Profile Analysis, LPA) has recently been developed to such an extent that it can be applied as a powerful method for the characterization of microstructures of crystalline materials in terms of crystallite ...
Gubicza, Jenő, Ungár, Tamás
core   +1 more source

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