Results 101 to 110 of about 2,526,322 (292)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

V1 clauses and EPP in Old Italian

open access: yesIsogloss
This work discusses some aspects of the so-called “relaxed verb-second hypothesis” for Old Romance languages focusing on Old Italian data. Although the idea that Medieval Romance varieties displayed some kind of verb-second grammar is often accepted in ...
Andrea Matticchio
doaj   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

On the cartography of Operator positions in Mocheno left periphery

open access: yes, 2009
In this paper I provide the first map of the Mòcheno left periphery. I show that this language should be considered a relaxed V2 language like Old Romance, but that, the fronted XP and the finite verb can move to two positions within the left periphery ...
COGNOLA, FEDERICA
core  

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

A Regional Core, Adjacent, Periphery Model for National Economic Geography Analysis [PDF]

open access: yes
and classifies a country’s regions into three types according to population density criteria. The regions within a country are typified as; core, adjacent, and periphery. The benefit of this classification is twofold.
Henk J.E.M. Brand
core  

The multifaceted roles of lysosomes in cancer

open access: yesMolecular Oncology, EarlyView.
Lysosomes support cancer cell adaptation by integrating macromolecule degradation and nutrient recycling with nutrient sensing, inter‐organelle communication and immune regulation. These interconnected functions can promote tumour growth, stress tolerance and therapy resistance, while also creating context‐dependent vulnerabilities that may be ...
Jia Li, Kevin M. Ryan
wiley   +1 more source

Main clause că ‘that’ in Romanian

open access: yesBucharest Working Papers in Linguistics, 2010
Romanian că ‘that’ is the Force head of subordinated clauses (Hill 2004). In this paper I point out that the complementizer că ‘that’ may occur in root (vs.
Virginia Hill
doaj  

Grasping and Pointing in Visual Periphery: Consistent Impairments in Visual form Agnosic Patient DF

open access: yesi-Perception, 2013
In a recent study, we observed that the visuomotor performance of visual form agnosic patient DF is significantly impaired when targets are presented in visual periphery (Hesse, Ball, & Schenk, 2012).
C Hesse, T Schenk
doaj   +1 more source

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