Results 81 to 90 of about 221,060 (301)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
The syntax of orientation shifting: Evidence from English high adverbs
, 2014 This paper reviews new data supporting the inclusion of a Speech Act Phrase in the left periphery. Illocutionary and evidential adverbs in English shift orientation from speakers in declarative sentences to addressees in yes-no interrogative sentences ...
Woods, Rebecca
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Unexpected Finding in Ocular Surface Trauma: A Large Intraorbital Foreign Body (Bullet)
Acta Medica, 2012 Sometimes intraorbital foreign bodies lead to unexpected findings. A 16-year old boy was referred due to ocular surface trauma. A conjunctival laceration was detected at the level of the left caruncle with associated left exotropia, reduced adduction as ...
Efstathios T. Detorakis +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
The Syntax of Left Periphery in Arabic A Minimalist Analysis [PDF]
, 2016 This thesis investigates the syntax of the left periphery in two varieties of Arabic, Modern Standard Arabic and Tabuki Arabic. The thesis adopts the Split-CP hypothesis proposed by Rizzi (1997) and the minimalist theoretical framework proposed by ...
Alatawi, Swailem
core
The phonological status of initial peaks in European Portuguese
Catalan Journal of Linguistics, 2003 This paper investigates the phonology of initial peaks in European Portuguese intonation. Evidence is presented for two types of peaks: an accentual peak, that is consistently aligned relative to the first stressed syllable; and a phrasal peak, that is ...
Sónia Frota
doaj +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
On a-Marking Topics in the Italian Left Periphery
, 2018 In Italian Clitic Left Dislocated/ClLD structures in which the left dislocated topic is the direct object of the following clause, such object noun phrase may sometimes be introduced by preposition a.
Adriana Belletti
core +1 more source
Discourse particles in the left periphery
ZAS Papers in Linguistics, 2004 This article analyses the German discourse particle wohl 'I suppose', 'presumably' as a syntactic and semantic modifier of the sentence types declarative and interrogative. It is shown that wohl does not contribute to the propositional, i.e. descriptive content of an utterance. Nor does it trigger an implicature.
openaire +2 more sources