Results 71 to 80 of about 2,526,322 (292)
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise +5 more
wiley +1 more source
Les questions en grammaire générative
In this chapter, we address the generative approach to interrogative structures, mostly under the Principles & Parameters framework. After a brief theoretical overview, we discuss direct open and closed questions, then embedded questions, showing how I ...
Jean-Charles KHALIFA
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
The Layered Syntactic Structure of the Complementizer System: Functional Heads and Multiple Movements in the Early Left-Periphery. A Corpus Study on Italian. [PDF]
Moscati V, Rizzi L.
europepmc +1 more source
Clitics and the Left Periphery in Cayuga
We propose that pronominal markers in Cayuga are clitics that obey an updated version of the Tobler-Mussafia Law. Specifically, pronominal markers cannot appear at the left edge of an Intonational Phrase and undergo prosodic inversion at PF if they appear in that position at Spell-Out. This analysis has two important implications.
null Barrie Michael Jonathan Mathew +2 more
openaire +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
On a-Marking Topics in the Italian Left Periphery
In Italian Clitic Left Dislocated/ClLD structures in which the left dislocated topic is the direct object of the following clause, such object noun phrase may sometimes be introduced by preposition a.
Adriana Belletti
core +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Demystifying “Stylistic Fronting” in Medieval French
This study re-examines the phenomenon traditionally termed Stylistic Fronting (SF) in Medieval French. Drawing on data from verse texts dating from the thirteenth to the fourteenth centuries, it investigates the syntactic distributions and pragmatic ...
Dong Hyun Kang
doaj +1 more source

