Results 71 to 80 of about 314,678 (294)

Illusionism and the Epistemological Problems Facing Phenomenal Realism [PDF]

open access: yes, 2016
Illusionism about phenomenal properties has the potential to leave us with all the benefit of taking consciousness seriously and far fewer problems than those accompanying phenomenal realism.
Ross, Amber
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Three Metaphors toward a Conception of Moral Change

open access: yesNordic Wittgenstein Review, 2018
Contemporary moral philosophy is split between an inherently a-historical moral philosophy/theory on the one hand and a growing interest in moral history and the historicity of morality on the other.
Nora Hämäläinen
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

The New Left. 1968 and Post Scriptum

open access: yesRevista Mexicana de Ciencias Políticas y Sociales, 2018
INTRODUCTORY NOTE The author, a well know theorist and activist of the civil rights movement and the movement against the Vietnam War, published the first part of this article from his own intervention and experience in 1968.
Michael Walzer
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

O historiador e o teórico: a historiografia de Hobbes na teoria das relações internacionais The historian and the theoretician: Hobbes' historiography in the theory of international relations

open access: yesContexto Internacional, 2003
Uma dificuldade crucial no estudo das relações internacionais é unir investigação teórica com investigação histórica. O objetivo deste artigo é analisar como Hobbes enfrentou este problema, bem como em que medida a solução que apresentou influenciou a ...
Soraya Nour, Claus Zittel
doaj   +1 more source

LEFT REALISM CRIMINOLOGY: BASIS AND PERSPECTIVES

open access: yesKnowledge International Journal, 2019
Left realism emerges in the early 1980s as a separate department, or direction within the neo-Marxist critical criminology. It results from dissatisfaction and certain criticisms of the foundations on which critical criminology is built, which left realists call left idealism.
openaire   +1 more source

Minimum Detection Efficiencies for a Loophole-Free Bell-type Test

open access: yes, 2009
We discuss the problem of finding the most favorable conditions for closing the detection loophole in a test of local realism with a Bell inequality. For a generic non-maximally entangled two-qubit state and two alternative measurement bases we apply ...
G. Garbarino, J. S. Bell, W. Rosenfeld
core   +1 more source

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