Results 91 to 100 of about 314,678 (294)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Las novelas de Alberto Vanasco: en la estela del surrealismo

open access: yesRecial, 2014
The paper proposes a reading of Alberto Vanasco’s novelistic work. It focuses on the tension between the avant-garde procedures and the realistic demands of the novel form.
Rafael Arce
doaj  

Age-related changes in time perception: Effects of immersive virtual reality and spatial location of stimuli

open access: yesActa Psychologica
The perception of time is subject to various environmental influences and exhibits changes across the lifespan. Studies on time perception have often been conducted using abstract stimuli and artificial scenarios, and recent claims for more naturalistic ...
Johanna Bogon   +3 more
doaj   +1 more source

Literature and National Consciousness of the Greek Minority in NorthernEpirus

open access: yesHistorical Review, 2007
The first period of Albanian rule in Northern Epirus, from 1912 to 1945, witnessed a continuation of the oral tradition enriched by the experience of the unceasing struggle for liberation.
Anteia Frantzi
doaj   +1 more source

“In Pursuit Of Purified Persuasions”: Making (Some) Sense of the Modern Mind [PDF]

open access: yes, 2015
What is more essential to the philosophical act, what we study or how we study? Taking its cue from a line by Thomas Aquinas on the corruptibility of the natural law, this essay seeks to make some sense of the ways in which our way of knowing and ...
Clarke, John Emmet
core   +1 more source

Texture Mixer: A Network for Controllable Synthesis and Interpolation of Texture

open access: yes, 2019
This paper addresses the problem of interpolating visual textures. We formulate this problem by requiring (1) by-example controllability and (2) realistic and smooth interpolation among an arbitrary number of texture samples.
Amirghodsi, Sohrab   +4 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

3-D immersive screen experiments [PDF]

open access: yes, 2010
We are currently piloting a range of computer simulated science experiments as 3-D virtual environments. These are rendered on a PC in 3-D and use photographs of specic parts of the actual apparatus as textures to add realism to the simulation.
Lucas, Robert
core  

Relativity, Anomalies and Objectivity Loophole in Recent Tests of Local Realism

open access: yes, 2017
Local realism is in conflict with special quantum Bell-type models. Recently, several experiments have demonstrated violation of local realism if we trust their setup assuming special relativity valid.
Bednorz, Adam
core   +2 more sources

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