Results 111 to 120 of about 1,977,355 (211)

Scientific Realism and High-Energy Physics

, 2017
The article discusses the implications of high-energy physics for the scientific realism debate. After a brief introduction to high-energy physics, the anti-realist import of the erosion of intuition-based concepts in the context of high-energy physics ...
Dawid, Richard,, Richard Dawid
core   +1 more source

Art of urgency. Contributions to the Critical Debate of the Spanish Civil War Propaganda art.

Cuadernos de Arte de la Universidad de Granada, 2016
The concept «arte de urgencia» defined, during the Spanish Civil War propaganda art, the artistic practice of agit-prop of Leninist inspiration. This article provides a critical review of the debate held by the artists and writers to the dissatisfaction ...
Miguel Ángel Gamonal Torres
doaj  

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Critical Realism in Economics and Open-Systems Ontology: A Critique [PDF]

This paper examines the treatment of ontology offered by Critical Realism. Three main criticisms are made of the Critical Realist treatment of open systems.
Andrew Mearman
core  

Inconsistency and Scientific Realism [PDF]

, 2013
I erect a framework within the semantic view of theories for explaining the empirical success of internally inconsistent models and theories, with scientific realism in mind.
Saatsi, Juha
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Prototyping and Evaluating TWIRL: A Temperature-Controlled DIY Airflow System for Enhancing Immersive Media

Journal on Interactive Systems
This study presents the design, prototyping, and user-centered evaluation of TWIRL (Thermal Wind Right and Left), a low-cost, temperature-controlled airflow system aimed at enhancing immersion in multisensory media experiences.
Aleph Campos da Silveira, Eduardo Correa Rodrigues, Estevao Bissoli Saleme, Alexandra Covaci, Gheorghita Ghinea, Celso Alberto Saibel Santos   +5 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Critical Realism, Gender and Feminism : Exchanges, Challenges, Synergies

, 2016
Editorial to the special issue of JCR on Critical Realism, Gender and ...
Gunnarsson, Lena,, van Ingen, Michiel,, Martínez Dy, Angela,   +2 more
core   +1 more source