Results 31 to 40 of about 147,367 (260)

Cardiac structure and function in relation to cardiovascular risk factors in Chinese

open access: yesBMC Cardiovascular Disorders, 2012
Background Cardiac structure and function are well-studied in Western countries. However, epidemiological data is still scarce in China. Methods Our study was conducted in the framework of cardiovascular health examinations for the current and retired ...
Zhang Yi   +5 more
doaj   +1 more source

Acute Endocrine Alterations After Traumatic Brain Injury and 6‐Month Functional Outcome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Acute multi‐axis endocrine alterations after traumatic brain injury (TBI) remain incompletely characterized. This study aimed to examine their temporal patterns and explore their associations with 6‐month functional outcome and early inflammatory markers.
Biao Xu   +9 more
wiley   +1 more source

Topically Delivered Treg‐Attracting Microparticle‐Hydrogel Composites Recruit Regulatory T Cells and Limit Cardiac Injury After Severe Ischemia

open access: yesAdvanced Healthcare Materials, EarlyView.
CCL22‐releasing PLGA microparticles (MP) suspended in topically applied hydrogels (HEART) establish a sustained chemokine gradient at the injured myocardium. HEART recruits CCR4+ regulatory T cells, reduces infarct size and graft fibrosis, and improves cardiac function.
Matthew A. Borrelli   +8 more
wiley   +1 more source

Effect of maintenance hemodialysis on diastolic left ventricular function in end-stage renal disease

open access: yesClinics, 2010
PURPOSE: To analyze the effect of maintenance hemodialysis on left ventricular diastolic function in patients with end-stage renal disease. METHODS: Study population consisted of 42 patients with end-stage renal disease.
Mustafa Duran   +5 more
doaj   +1 more source

Pre-operative evaluation and mid-term outcomes of anomalous origin of the left coronary artery from the pulmonary artery based on left ventricular ejection fraction

open access: yesFrontiers in Cardiovascular Medicine, 2022
ObjectiveThe purpose of this study was to evaluate the prognosis of patients with anomalous left coronary artery originating from pulmonary artery with varying cardiac function after surgical correction.MethodsThis was a single-center retrospective ...
Shu-Liang Xia   +21 more
doaj   +1 more source

Synchronization‐Dissipation in the Cardiorespiratory System

open access: yesAdvanced Science, EarlyView.
By modeling central nervous coupling and viscoelastic interactions in the cardiorespiratory system we show that synchronization produces a 10% gain in cardiac efficiency in humans. It is surmised that respiratory sinus arrhythmia improves cardiac pumping efficiency by reducing dynamic stress and power dissipation in the pulmonary vasculature.
Joshua R. Border   +3 more
wiley   +1 more source

SR‐A3 Promotes USP18‐Mediated deISGylation of STING to Protect Against Myocardial Ischemia‐Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
MI/RI is a major clinical challenge with high morbidity and mortality. This study demonstrates that SR‐A3 expression is downregulated in MI/RI, and its deletion exacerbates damage via the USP18/ISG15/STING axis, revealing SR‐A3 as a potential therapeutic target.
Yufei Han   +24 more
wiley   +1 more source

Diastolic cardiac function in connective tissue dysplasia

open access: yesЛечащий Врач, 2021
The article analyzes literature data on the diagnostics of diastolic function condition in young patients with signs of connective tissue dysplasia. The problem of diagnostics of pre-clinical left-ventricular diastolic dysfunction was discussed, as well ...
Yu. V. Tereschenko   +6 more
doaj  

Echocardiographic assessment of left cardiac structure and function in antiretroviral therapy (ART)‐naïve people living with HIV/AIDS

open access: yesImmunity, Inflammation and Disease, 2023
Background Patients with human immunodeficiency virus (HIV) are at a significantly higher risk of cardiovascular disease (CVD) compared to HIV‐negative people.
Xing Hu   +6 more
doaj   +1 more source

SerpinA3 is an Endogenous TGF‐β Receptor Antagonist that Attenuates Cardiac Fibroblast Activation and Fibrotic Remodeling

open access: yesAdvanced Science, EarlyView.
SerpinA3 acts as an endogenous TGF‐β receptor antagonist that binds to the extracellular domain of TGFR‐1, thereby preventing TGFR‐1–TGFR‐2 complex formation. This receptor‐level blockade suppresses TGF‐β/Smad2/3 signaling, attenuates cardiac fibroblast activation, and extracellular matrix deposition, and ultimately alleviates pressure overload–induced
Hui Wang   +9 more
wiley   +1 more source

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