Results 41 to 50 of about 147,367 (260)

Left atrial stiffness index – an early marker of left ventricular diastolic dysfunction in patients with coronary heart disease

BMC Cardiovascular Disorders
Aims To evaluate the correlation between left atrial stiffness index (LASI) and left ventricular diastolic function in patients with coronary heart disease (CHD) by Autostrain LA technique.
Yingxuan Tu, Xin Liu, Xiaoqing Li, Na Xue   +3 more
doaj   +1 more source

Left Ventricular Diastolic Dysfunction in Liver Cirrhotic Patients: Proportion, Correlation, and Relationship of Diastolic Parameters with Stage of Liver Dysfunction

Jurnal Penyakit Dalam Indonesia, 2018
Introduction. Cardiovascular complication of liver cirrhosis is relatively obscure. Pathophysiology of liver cirrhosis, involving portal hypertension made the possibility of cirrhosis complication manifested as left ventricular diastolic dysfunction ...
Prionggo Mondrowinduro, Irsan Hasan, Idrus Alwi, Murdani Abdullah   +3 more
doaj   +1 more source

Left atrial size in patients with arterial hypertension [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2006
INTRODUCTION Left atrial size is increased in patients with arterial hypertension. Left atrial enlargement represents a risk factor of atrial fibrillation and stroke. Left atrial size depends on the effect of many other etiological factors, predominantly
Milutinović Suzana, Apostolović Svetlana, Tasić Ivan   +2 more
doaj   +1 more source

Proteogenomic Profiling of Idiopathic Pulmonary Arterial Hypertension Identifies Sex‐Differential Proteins and Candidate Therapeutic Targets

Advanced Science, EarlyView.
An integrated proteogenomic analysis of 44,137 predominantly European‐ancestry UK Biobank participants aged 40–69 years identifies 12 robust proteins associated with idiopathic pulmonary arterial hypertension. These proteins define a high‐mortality molecular endotype, support early detection and mortality prediction, reveal sex‐differential proteomic ...
Xinjie Lin, Yangchang Zhang, Yang Pu, Duanke Liu, Tao Lei, Kai Ma, Qiyu He, Zheng Dou, Yuze Liu, Dengyuan Liu, Yinge He, Yanshang Wang, Xiaojiao Zheng, Yanbing Ma, Jianrong Zhou, Weiding Zhai, Binbin Su, Li Chen, Shoujun Li   +18 more
wiley   +1 more source

Effect of Peritoneal Dialysis Treatment on Left Ventricular Systolic and Diastolic Functions in Patients with End-Stage Renal Disease

Turkish Journal of Nephrology, 2019
OBJECTIVE: To analyze the effect of peritoneal dialysis (PD) treatment on left ventricular systolic and diastolic function in patients with end-stage renal disease (ESRD).
Feridun KAVUNCUOĞLU, Oktay OYMAK, Bülent TOKGÖZ, Murat Hayri SİPAHİOĞLU, Havva CİLAN, Nilüfer OĞUZHAN, Mesut AKÇAKAYA, İsmail KOÇYİĞİT, Mustafa DURAN, Mikail YARLIOĞLUEŞ, Aydın ÜNAL, Cengiz UTAŞ   +11 more
doaj  

Effect of Body Mass Index on Left Ventricular Diastolic Function

Kufa Journal for Nursing Sciences, 2017
Introduction: Overweight and obese persons are at increased risk for heart failure. A direct effect of isolated obesity on cardiac function is not well established.
Mohammed H. Al-Meshhadani, Ahmed N. Rgeeb, Ammar Emad Ali   +2 more
doaj   +1 more source

An Extracellular Pore‑Targeting Peptide Defines a Designable Allosteric Site in TRPV2

Advanced Science, EarlyView.
Structure‐guided peptide engineering yields Depiv2, a highly potent and subtype‐selective TRPV2 inhibitor that binds to the extracellular pore and remodels it into a closed, non‐conductive state. Depiv2 suppresses pathological cardiac hypertrophy, establishing the TRPV2 outer pore as a designable interface for selective peptide modulation.
Aiqin Zhu, Hongkun Wang, Jiawei Wang, Xiaolu Liu, Aerziguli Aierken, Lizhen Xu, Ping Liang, Fan Yang   +7 more
wiley   +1 more source

Drug Repurposing for Treating NCOR‐Related Intellectual Disability

Advanced Science, EarlyView.
An autism‐associated NCOR1 heterozygous mutation upregulates NRGs and activates NRG backward signaling in hypothalamic GABAergic neurons in mouse models, leading to Gabra2 downregulation and cognitive deficits, which can be therapeutically targeted by repurposing FDA‐approved drugs.
Yan Kong, Wenjun Zhou, Yuxiang Sun, Zihan Huang, Zhiyue Liu, Udhaya Kumar. S, Chenyan Li, Yi Lu, Chengchuang Song, Veronica C. Ciliberto, Makenna Mack, Lana E. Kim, Zhaoyong Hu, Fang Luo, Aihua Cao, Zheng Sun   +15 more
wiley   +1 more source

Impact of overweight on left ventricular function in type 2 diabetes mellitus

Cardiovascular Diabetology, 2017
Background Coexistence of left ventricular (LV) longitudinal myocardial systolic dysfunction with LV diastolic dysfunction could lead to heart failure with preserved ejection fraction (HFpEF).
Makiko Suto, Hidekazu Tanaka, Yasuhide Mochizuki, Jun Mukai, Hiroki Takada, Fumitaka Soga, Kumiko Dokuni, Yutaka Hatani, Keiko Hatazawa, Hiroki Matsuzoe, Hiroyuki Sano, Hiroyuki Shimoura, Junichi Ooka, Kensuke Matsumoto, Yushi Hirota, Wataru Ogawa, Ken-ichi Hirata   +16 more
doaj   +1 more source

Comparison of two echocardiography-based methods for evaluating pediatric left ventricular diastolic dysfunction

Frontiers in Pediatrics, 2023
ObjectivesTo investigate the consistency between the 2016 America Society of Echocardiography (ASE)/European Association of Cardiovascular Imaging (EACVI) guideline-based recommendations and the body surface area (BSA)-transformed Z value-based cut-off ...
Xue Xiang, Xu Zhu, Min Zheng, Yi Tang
doaj   +1 more source