Results 161 to 170 of about 194,767 (337)

Single‐Cell Mitochondrial Lineage Tracing Decodes Fate Decision and Spatial Clonal Architecture in Human Hematopoietic Organoids

open access: yesAdvanced Science, EarlyView.
This study repurposes mitochondrial DNA mutations as endogenous barcodes for lineage tracing in human pluripotent stem cell‐derived organoids. Integrated with transcriptomic and spatial data, it reveals NOTCH‐mediated stromal‐progenitor crosstalk orchestrates clonal dynamics and spatial zonation during early hematopoietic development, offering a non ...
Yan Xue   +17 more
wiley   +1 more source

Left Ventricular Mass Index Predicts Pacemaker-Induced Cardiomyopathy in Patients with Dual Chamber Permanent Pacemakers Implanted Due to Complete Atrioventricular Block. [PDF]

open access: yesActa Cardiol Sin, 2023
Hayıroğlu Mİ   +9 more
europepmc   +1 more source

Association of inflammation with left ventricular mass index in patients with rheumatoid arthritis [PDF]

open access: bronze
Anja Linde   +7 more
openalex   +1 more source

Phocaeicola coprophilus‐Derived 6‐Methyluracil Attenuates Radiation‐Induced Intestinal Fibrosis by Suppressing the IDO1‐Kynurenine‐AHR Axis

open access: yesAdvanced Science, EarlyView.
IR‐induced dysbiosis depletes P. coprophilus and its metabolite 6‐methyluracil, leading to disinhibition of the IDO1‐Kyn‐AHR axis. This results in sustained fibroblast activation and collagen deposition, driving radiation induced intestinal fibrosis. ABSTRACT Therapeutic options for radiation‐induced intestinal fibrosis (RIF) remain limited. This study
Jiaxin Zhang   +11 more
wiley   +1 more source

Overweight and early heart remodelling in women with arterial hypertension

open access: yesКардиоваскулярная терапия и профилактика, 2010
Aim. To compare left ventricular (LV) remodelling and LV myocardial mass indices (MMI) in overweight and nonoverweight women with arterial hypertension (AH). Material and methods.
E. M. Khurs   +5 more
doaj  

Left ventricular mass index-to-QRS-voltage ratio predicts outcomes in heart failure with preserved ejection fraction. [PDF]

open access: yesESC Heart Fail, 2022
Kinugasa Y   +11 more
europepmc   +1 more source

Microgel‐Based Hierarchical Porous Hydrogel Patch with Adhesion and Resilience for Myocardial Infarction

open access: yesAdvanced Science, EarlyView.
This study develops a hierarchically porous hydrogel patch strategy (HPMP), based on gas‐shearing microfluidics and an aqueous two‐phase system to fabricate porous microgels as microgel‐based bioinks. The porous microgels with controllable porous structure exhibit excellent cellular behavior.
Ziyang Liu   +13 more
wiley   +1 more source

Independent risk factors of left ventricular hypertrophy in non-diabetic individuals in Sierra Leone - a cross-sectional study

open access: yesLipids in Health and Disease
Background Left ventricular hypertrophy (LVH) is a critical factor in heart failure and cardiovascular event-related mortality. While the prevalence of LVH in diabetic patients is well-documented, its occurrence and risk factors in non-diabetic ...
Yuanxin Xu   +7 more
doaj   +1 more source

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