Results 171 to 180 of about 194,767 (337)

Predicting one-year left ventricular mass index regression following transcatheter aortic valve replacement in patients with severe aortic stenosis: A new era is coming. [PDF]

open access: yesFront Cardiovasc Med, 2023
Asheghan MM   +9 more
europepmc   +1 more source

Chaperone‐Mediated Autophagic Degradation of USP9X in Macrophages Exacerbates Postmyocardial Infarction Inflammation and Cardiac Dysfunction

open access: yesAdvanced Science, EarlyView.
This study demonstrates that inflammatory stimuli induce the acetylation‐triggered, chaperone‐mediated autophagic degradation of ubiquitin‐specific peptidase 9 X‐linked (USP9X) in macrophages. USP9X acts as a macrophage “inflammation switch” after myocardial infarction (MI). USP9X loss destabilizes tumor necrosis factor receptor‐associated factor (TRAF)
Biqing Wang   +7 more
wiley   +1 more source

Tumor Extracellular Vesicles lncOSLMT Drives Lung Inflammatory Premetastatic Niche Formation in Osteosarcoma via m6A‐Dependent hnRNPA2B1/COX‐2 Axis

open access: yesAdvanced Science, EarlyView.
Tumor‐derived extracellular vesicles program inflammatory lung premetastatic niches through selective delivery of long noncoding RNAs. This work reveals EVs‐associated lncOSLMT as a key driver of lung fibroblast activation via m6A‐dependent PTGS2 stabilization.
Hongbo Li   +10 more
wiley   +1 more source

Low NT-proBNP levels in overweight and obese patients do not rule out a diagnosis of heart failure with preserved ejection fraction [PDF]

open access: yes, 2018
Background Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous syndrome that presents clinicians with a diagnostic challenge. The use of natriuretic peptides to exclude a diagnosis of HFpEF has been proposed.
Abbate, Antonio   +9 more
core   +1 more source

Intelligent Soft Opto‐Magnetic Robot for Minimally Invasive Interventional Therapy

open access: yesAdvanced Science, EarlyView.
An intelligent soft opto‐magnetic (iSOM) robot is developed that integrates remote magnetic actuation, skin‐mimic tactile perception, and photothermal ablation in a near‐millimeter‐scale design. It enables precise intraluminal navigation and localized ablation while providing real‐time optical feedback to support safe and accurate minimally invasive ...
Jingjing Guo   +13 more
wiley   +1 more source

Impact of left ventricular hypertrophy on frequency and complexity of ventricular arrhythmia among hypertensive Egyptian patients

open access: yesThe Egyptian Heart Journal
Background Left ventricular hypertrophy (LVH) is associated with an increased risk of ventricular arrhythmias and cardiovascular mortality. The study objective was to investigate the effect of LVH severity on the complexity and severity of ventricular ...
Ahmed Mokhtar Abd El Azeem   +3 more
doaj   +1 more source

Nocturnal blood pressure surge in seconds is a new determinant of left ventricular mass index. [PDF]

open access: yesJ Clin Hypertens (Greenwich), 2022
Kokubo A   +6 more
europepmc   +1 more source

Reconstructing Coherent Functional Landscape From Multi‐Modal Multi‐Slice Spatial Transcriptomics by a Variational Spatial Gaussian Process

open access: yesAdvanced Science, EarlyView.
This study introduces stVGP, a variational spatial Gaussian process framework for multi‐modal, multi‐slice spatial transcriptomics. By integrating histological and genomic data through hybrid alignment and attention‐based fusion, stVGP reconstructs coherent 3D functional landscapes.
Zedong Wang   +3 more
wiley   +1 more source

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