Results 51 to 60 of about 397,523 (260)

Internal consistency and reliability of the Swiss-French translation of the venous leg ulcer self efficacy tool (VeLUSET)

BMJ Open, 2019
Objective This study was conducted to assess the psychometric properties of the translated and adapted Venous Leg Ulcer Self Efficacy Tool (VeLUSET) in the new cultural context.Design Validation studySetting Three outpatient clinics in Western ...
Sebastian Probst, Mathieu Turcotte, Monika Buehrer Skinner   +2 more
doaj   +1 more source

Pembrolizumab‐Induced Subacute Cutaneous Lupus Erythematosus: A Case Report

JEADV Clinical Practice, EarlyView.
ABSTRACT Subacute cutaneous lupus erythematosus (SCLE) is an increasingly recognized cutaneous immune‐related adverse event of immune checkpoint inhibitors. We report an 83‐year‐old woman who developed pruritic annular and polycyclic plaques 10 weeks after starting pembrolizumab for oropharyngeal squamous cell carcinoma.
Sebastiano Posenato, Alba Guglielmo, Lucia Mantovani, Aikaterini Kalpaktsoglou, Simone Cavaliere, Alessandro Borghi   +5 more
wiley   +1 more source

Fear‐Avoidance and Overactive Bladder: Toward a Mechanism‐Informed Model of Care

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims Overactive bladder (OAB) is associated with substantial psychological burden, yet existing biopsychosocial frameworks acknowledge that psychological factors shape outcomes without explaining the cognitive and behavioral mechanisms through which that influence operates.
Rupal M. Patel, Andrea Wood
wiley   +1 more source

Feasibility of a prospective cohort study to support future investigation of prognostic factors for venous leg ulcer healing

BMJ Open
Objectives To evaluate the feasibility of recruitment, longitudinal clinical data collection and repeated dressing-sample collection within routine NHS community venous leg ulcer centres, to inform a future larger prospective cohort study evaluating ...
Jo C Dumville, Adam J Reid, Sara Lloyd-John, Joe Harvey, Nichola J Barron, Rachel E B Watson, Jason K F Wong, Sarah E Herrick   +7 more
doaj   +1 more source

Feasibility and Exploratory Outcomes of Foot‐Ankle and Walking Exercises for Diabetic Neuropathy, Stress, and Quality of Life: A Pilot Randomized Controlled Trial

Research in Nursing &Health, EarlyView.
ABSTRACT Foot–ankle and walking exercises have been proposed as potential strategies for managing symptoms in people with diabetic peripheral neuropathy (DPN), yet evidence from primary care remains limited. This pilot study assessed the feasibility and acceptability of these interventions and explored preliminary outcome patterns in DPN, stress, and ...
Siti Fadlilah, Wahyu Rochdiat Murdhiono, Ariyanto Nugroho, Yohanes Andy Rias, Shih Hsin Hsiao, Kai Ling Lee, Po Hao Feng, Hsiu Ting Tsai   +7 more
wiley   +1 more source

Evaluation of Platelet-rich Fibrin Matrix Dressings in Patients with Chronic Nonhealing Leg Ulcers

Journal of Dermatology and Dermatologic Surgery
Background: Chronic nonhealing ulcers of the lower extremity are a cause of morbidity and mortality. Platelets are cells that play a central role in wound healing, and they are the main source of the growth factor complex that plays the main role in ...
Shishira R. Jartarkar, Varun C. Katti, Konduru Sanjana Raju   +2 more
doaj   +1 more source

VenUS IV (Venous leg Ulcer Study IV) – compression hosiery compared with compression bandaging in the treatment of venous leg ulcers: a randomised controlled trial, mixed-treatment comparison and decision-analytic model

Health Technology Assessment, 2014
Background: Compression is an effective and recommended treatment for venous leg ulcers. Although the four-layer bandage (4LB) is regarded as the gold standard compression system, it is recognised that the amount of compression delivered might be ...
Rebecca L Ashby, Rhian Gabe, Shehzad Ali, Pedro Saramago, Ling-Hsiang Chuang, Una Adderley, J Martin Bland, Nicky A Cullum, Jo C Dumville, Cynthia P Iglesias, Arthur R Kang’ombe, Marta O Soares, Nikki C Stubbs, David J Torgerson   +13 more
doaj   +1 more source

Sickle Cell Disease: Historical Overview and Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide, yet the limited treatment options currently available do not always adequately control the disease and carry significant side effects. At present, the only curative treatment is hematopoietic stem cell (HSC) transplantation, a procedure that carries considerable challenges and numerous ...
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

Genomics and epigenomics of tissue repair: Implications for personalized medicine

Precision Medical Sciences, EarlyView.
Genomic and epigenomic mechanisms govern tissue repair and regeneration through dynamic regulation of inflammation, cell fate, and extracellular matrix remodeling. The integration of multi‐omics, artificial intelligence, and precision regenerative therapies enables biomarker‐driven, personalized approaches to enhance healing and minimize fibrosis ...
Jharna Medhi, Chandrashekar Thalluri, Sarad Pawar Naik Bukke, Piyali Dey, Mallikarjun Vasam, Ananda Kumar Chettupalli, Swetha Kumari Koduru, Gali Avinash Kumar   +7 more
wiley   +1 more source

Potential of Ginkgo biloba Extract to Intervene in Chronic Inflammation‐Related Diseases

Phytotherapy Research, EarlyView.
Chronic inflammation is a pathological mechanism underpinning many diseases. Ginkgo biloba extract (GBE) is well known for its anti‐inflammatory property. GBE and its active constituents have been shown to attenuate pro‐inflammatory cytokine production, suppress nuclear factor kappa B activation, restore redox homeostasis, and modulate disease‐relevant
Yipeng Lin, Inho Cho, Xue Zhu, Ke Wang, Ling Zhu, Wenchang Wong, Michael Murray, Fanfan Zhou   +7 more
wiley   +1 more source