A 71 year old female Caucasian farmer without any known immunosuppression presented with a painful ulcer of her right lower leg after a trauma caused by a wood billet. There was no response to empirical antibacterial treatment.
Philipp Jud +7 more
doaj +1 more source
Diagnostic implications and correlates of plasma ADA2 activity and ADA2 variants
Objectives Deficiency of adenosine deaminase 2 (DADA2) is a monogenic autoinflammatory disease manifested as polyarteritis nodosa, stroke, and bone marrow failure. Leveraging an international cohort of 200 DADA2 cases, we aimed to characterize the diagnostic utility of a plasma ADA2 enzyme activity assay and understand the implications of residual ADA2
Jian Yue +55 more
wiley +1 more source
Clinical usage of honey as a wound dressing: An update [PDF]
Honey is an ancient treatment that is increasingly earning its place in modern wound care. Evidence suggests it compares with other dressings in terms of its antibacterial properties, ease of use and ability to promote a moist ...
Molan, Peter C.
core +2 more sources
Evaluation of Platelet-rich Fibrin Matrix Dressings in Patients with Chronic Nonhealing Leg Ulcers
Background: Chronic nonhealing ulcers of the lower extremity are a cause of morbidity and mortality. Platelets are cells that play a central role in wound healing, and they are the main source of the growth factor complex that plays the main role in ...
Shishira R. Jartarkar +2 more
doaj +1 more source
Ehlers-Danlos Syndrome Type VIII: A Rare Cause of Leg Ulcers in Young Patients
Ehlers-Danlos syndrome type VIII (EDS-VIII) is a very rare autosomal dominant disease characterized by early-onset periodontitis associated with features of Ehlers-Danlos syndrome.
Sophie Ronceray +6 more
doaj +1 more source
Pulmonary hypertension in patients with Martorell hypertensive leg ulcer: a case control study
Background Martorell hypertensive ischemic leg ulcer (Martorell ulcer) is characterized by distinct alterations in the arteriolar wall of subcutaneous vessels, leading to progressive narrowing of the vascular lumen and increase of vascular resistance ...
Glutz von Blotzheim Leonardo +8 more
doaj +1 more source
Aims The aim of this study was to determine the purpose and use of physical examination (PE) in phase 3 and 4 drug interventional clinical trials within type 2 diabetes mellitus. Methods A total of 226 clinical trial protocols identified from the ClinicalTrials.gov database were systematically reviewed by five researchers.
Julia Kopanz +9 more
wiley +1 more source
The Efficacy of Pressure Ulcer Treatment With Cathodal and Cathodal-Anodal High-Voltage Monophasic Pulsed Current: A Prospective, Randomized, Controlled Clinical Trial [PDF]
Background. Studies show that anode and cathode electrical stimulation (ES) promotes the healing of wounds, but specific protocols for both electrodes are not available. Objective. To compare the effectiveness of cathodal versus cathodal+anodal ES in the
Blaszczak, Edward +8 more
core +2 more sources
The Effect of Vacuum Compression Therapy on Diabetic Foot ulcer
• Background:Recent studies indicate that vacuum compression therapy (VCT) of the foot may offer benefits in patients with intermittent claudication through improving arterial and venous blood flow.
Mojtaba Heshmatipour +2 more
doaj +1 more source
The use of biatain Ag in hard-to-heal venous leg ulcers: meta-analysis of randomised controlled trials. [PDF]
BACKGROUND: Venous leg ulcers are common, troublesome, and their failure to heal is often related to a heavy bio-burden. Ionized silver has both anti-inflammatory and antimicrobial properties.
David Leaper +6 more
doaj +1 more source

