Results 31 to 40 of about 5,896,523 (307)

Garden State Legacy no. 43 [PDF]

open access: yes, 2019
Garden State Legacy, no.

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Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Legacy Emanuel community health improvement plan

open access: yes, 2021
Title from PDF cover (viewed on March 31, 2022).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

A Learning Ecosystem for Linemen Training based on Big Data Components and Learning Analytics [PDF]

open access: yesJournal of Universal Computer Science, 2019
Linemen training is mandatory, complex, and hazardous. Electronic technologies, such as virtual reality or learning management systems, have been used to improve such training, however these lack of interoperability, scalability, and do not exploit trace
Guillermo Santamaría-Bonfil   +3 more
doaj   +3 more sources

Garden State Legacy no. 44 [PDF]

open access: yes, 2019
Garden State Legacy no.

core  

Legacy Meridian Park community health improvement plan

open access: yes, 2021
Title from PDF cover (viewed on March 31, 2022).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Modernization Solution for Legacy Banking System Using an Open Architecture [PDF]

open access: yesInformatică economică, 2012
Banks are still using legacy systems as the core of their business is comprised within such sys-tems. Since the technology and client demands are changing rapidly, the banks have to adapt their systems in order to be competitive. The issue is to identify
Constantin Marian MATEI
doaj  

Legacy Mount Hood community health improvement plan

open access: yes, 2021
Title from PDF cover (viewed on March 31, 2022).This archived document is maintained by the State Library of Oregon as part of the Oregon Documents Depository Program.

core  

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